A bacterial remnant may explain arthritis in Lyme patients

New Yale research offers insight into why some Lyme disease patients continue to suffer from debilitating arthritis even after antibiotic treatment.
Source: Yale Science and Health News - Category: Universities & Medical Training Source Type: news

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(Virginia Tech) With a $661,216 grant from the Steven&Alexandra Cohen Foundation, Brandon Jutras, an assistant professor of biochemistry in the Virginia Tech College of Agriculture and Life Sciences, will study Lyme arthritis, including the cellular component that contributes to it.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
(Washington State University) The next time a tick feeds on you, Washington State University researchers hope to make sure persistent arthritis caused by Lyme disease doesn't linger for a lifetime.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Purpose of review Lyme disease is an important, vector-borne infection found throughout the temperate Northern hemisphere. The disease causes rash, acute systemic illness, and in some untreated patients, inflammatory arthritis. This review examines the emergence, clinical features and management of early Lyme disease and Lyme arthritis. Recent findings There has been continuing progress in characterizing the clinical manifestations, diagnostic testing and treatment of Lyme disease. Almost all patients with early Lyme disease can be cured with antibiotic treatment. In most cases, Lyme arthritis also responds to antibio...
Source: Current Opinion in Rheumatology - Category: Rheumatology Tags: CLINICAL THERAPEUTICS AND HEMATOLOGIC COMPLICATIONS: Edited by W. Joseph McCune Source Type: research
Publication date: 17 March 2020Source: Cell Reports, Volume 30, Issue 11Author(s): Abdul G. Lone, Troy Bankhead
Source: Cell Reports - Category: Cytology Source Type: research
(Natural News) Lyme disease is one of the most common vector-borne diseases in the US. The CDC reports that around 30,000 Americans get infected by Lyme every year. However, other data gathering methods suggest that this number can rise to 300,000 cases each year. Because of the rising number of Lyme disease cases, scientists have...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
AbstractPurpose of ReviewSince recognition in 1975, Lyme disease has become the most common vector-borne illness in North America and Europe. The clinical features are well-characterized and treatment is usually curative, but misperceptions about morbidity persist. The purpose of this review is to examine advances in the diagnosis and treatment of Lyme disease, as well as ongoing management challenges.Recent FindingsIt is useful to recognize that Lyme disease occurs in stages, with early- and late-stage disease. Clinical expression is in part determined by Borrelial variability. For example, some strains ofBorrelia burgdor...
Source: Current Rheumatology Reports - Category: Rheumatology Source Type: research
NEW YORK (Reuters Health)—In Lyme disease-endemic areas, a C6 peptide enzyme immunoassay (EIA) test may help guide initial management of children with acute arthritis, an observational study suggests.1 “Children with Lyme disease frequently present to the emergency department with an inflamed joint,” Lise Nigrovic, MD, MPH, of Boston Children’s Hospital tells Reuters Health by email.... [Read More]
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions assay C6 peptide enzyme immunoassay (EIA) Lyme arthritis Lyme Disease Source Type: research
In Lyme disease-endemic areas, a C6 peptide enzyme immunoassay (EIA) test may help guide initial management of children with acute arthritis, an observational study suggests.Reuters Health Information
Source: Medscape Orthopaedics Headlines - Category: Orthopaedics Tags: Pediatrics News Source Type: news
Conclusions: A significant increase (P = .02) in Lyme arthritis cases was observed at Oishei Children's Hospital of Buffalo. Lyme arthritis may clinically present similarly to other forms of arthritis, such as oligoarticular juvenile idiopathic arthritis, so health care providers should be aware of distinguishing clinical features, which include rapid onset of swelling and patient age. Because the geographic area of endemic Lyme disease is expanding, all health care providers need to be aware of Lyme arthritis as a possible diagnosis. PMID: 31819695 [PubMed]
Source: Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders - Category: Orthopaedics Tags: Clin Med Insights Arthritis Musculoskelet Disord Source Type: research
ConclusionThis study of the clinical spectrum of LD in Canadian children underlines the need for preventive measures to protect children in Canada from emerging LD, and the need for health care provider awareness.
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
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