Gastric surgery increases risk of drug or alcohol-related death

According to a study, published inSurgery for Obesity and Related Diseases, alcohol and drug related deaths are much higher in gastric bypass patients, which may be a result of altered metabolism.Web MD
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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In the current manuscript (1) the authors reported the results of diagnostic upper endoscopy for a cohort of 250 consequent patients who presented with complaints after Roux en Y gastric bypass (RYGB). Ninety-eight patients (39.2%) with a relevant finding at upper endoscopy were identified, mostly marginal ulcer and stomal stenosis. The postoperative endoscopic findings can help us better understand long term complications following bariatric surgery. The authors should be commended for identifying risks factors to an abnormal upper endoscopy (male sex, smoking, alcohol consumption, referral reason and prior imaging studies).
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
AbstractIntroductionTransient tissue elastography (TTE) may estimate the degree of hepatic fibrosis in patients with obesity, but the method has restrictions that are mainly related to patients ’ BMI.PurposeTo compare the results of the evaluation of hepatic fibrosis by biochemical methods and TTE with those determined by liver biopsy in patients after RYGB.MethodsThis was a cross-sectional study involving patient data, TTE, and liver biopsy 1  year after RYGB.ResultsOf the 94 selected patients, 33 underwent TTE and liver biopsy. The average weight of patients was 84.4  ± 15.4 kg. The m...
Source: Obesity Surgery - Category: Surgery Source Type: research
Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), the most common bariatric surgeries performed worldwide, increase the risk to develop an alcohol use disorder (AUD). This might be due, in part, to surgery-related changes in alcohol pharmacokinetics. Another risk factor, unexplored within this population, is having a reduced subjective response to alcohol ’s sedative effects.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
After Roux-n-Y gastric bypass (RYGB) patients are at higher risk of alcohol problems. In recent years, sleeve gastrectomy (SG) has become a common procedure, but the incidence rates of alcohol abuse following SG are unexplored.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
We begin by complimenting Wang et al. for their research into treatment of Non-Alcoholic Fatty Liver Disease (NAFLD) after Roux-en-Y Gastric Bypass (RYGB) and Laparoscopic Sleeve Gastrectomy (LSG) through the analysis of Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) values at different timepoints. This is a burgeoning field of research, as NAFLD rates continue to rise globally. Bariatric surgery has been proven in numerous studies to improve AST and ALT values after bariatric surgery (1).
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Letter to the Editor Source Type: research
Abstract Bariatric surgery is the most effective treatment for severe obesity and its related comorbidities. Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) are currently the most popular weight-loss surgeries used worldwide. Following these surgeries, many patients self-report changes in taste perception and decreased preference for unhealthy foods. These reported changes might account for increased adherence to healthier diets and successful weight loss after surgeries. However, researchers have used a variety of methodologies to assess patients' reported changes andresults are discrepant. The goal o...
Source: Appetite - Category: Nutrition Authors: Tags: Appetite Source Type: research
Publication date: Available online 2 August 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): Jérémie Thereaux, Thomas Lesuffleur, Sébastien Czernichow, Arnaud Basdevant, Simon Msika, David Nocca, Bertrand Millat, Anne Fagot-CampagnaSummaryBackgroundConcerns are rising about the late adverse events following gastric bypass and sleeve gastrectomy. We aimed to assess, over a 7-year period, the late adverse events after gastric bypass and sleeve gastrectomy compared with matched control groups.MethodsIn this nationwide, observational, population-based, cohort study, we used data extracted from ...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
Abstract Alcohol and the Bariatric Patient: When One Drink Becomes Two Drinks Abstract. Moderate consumption of alcohol is a risk factor for weight gain and obesity. Alcohol affects all components of the energy balance. Alcohol consumption is - as in the general population - also a widespread phenomenon in obese and bariatric patients. As a function of the bariatric surgery technique, alcohol metabolism is altered: gastric bypass surgery and sleeve gastrectomy lead to a faster absorption of alcohol, higher peak alcohol concentration and a longer alcohol persistence in the circulation. Further reward mechanisms for...
Source: Praxis - Category: General Medicine Authors: Tags: Praxis (Bern 1994) Source Type: research
AbstractReductions in addiction-like food behaviors and increases in alcohol intake have been reported after weight loss surgery. However, no studies have tracked these measures in combination and prospectively. In this preliminary study, 27 participants underwent bariatric surgery (Roux-en-Y gastric bypass (RYGB) (n = 10) and sleeve gastrectomy (SG) (n = 6)), dietary weight loss (n = 6), or no treatment (n = 5). Participants were weighed, completed the Yale Food Addiction Scale (YFAS), and reported alcohol intake frequency before intervention and at 4 and 24 months afte...
Source: Obesity Surgery - Category: Surgery Source Type: research
This study used prospectively collected data from a state-wide quality collaborative. The presence of AUD was determined using the Alcohol Use Disorders Identification Test for Consumption (AUDIT-C), with a score  ≥ 4 in men and ≥ 3 in women suggestive of AUD. We used bivariate Chi-square tests for categorical variables and independent samplest tests for continuous variables. We used multivariable logistic regression to identify patient characteristics that may predispose patients to development of AUD at 1 and 2  years after surgery.ResultsThe overall prevalence of AUD in our population (n&...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
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