Flavonoid-derived privileged scaffolds in anti-Trypanosoma brucei drug discovery.

CONCLUSION: According to in vitro anti-T brucei studies, there is evidence that flavonoids might be lead compounds for the potential treatment of HAT. However, toxicological studies, as well as mechanism of action of the in vitro active flavonoids are needed to support their use as potential leads for the treatment of HAT. PMID: 31215385 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31215385?dopt=Abstract

Source: Current Drug Targets - June 17, 2019 Category: Drugs & Pharmacology Authors: Boniface PK, Elizabeth FI Tags: Curr Drug Targets Source Type: research