Heritability of glaucoma and glaucoma-related endophenotypes: Systematic review and meta-analysis
We have systematically extracted all available heritability (h2) estimates of glaucoma and related endophenotypes from the literature, and summarize the evidence by meta-analysis.Glaucoma endophenotypes were classified into 10 clusters: intraocular pressure (IOP), anterior chamber size (ACS), central corneal thickness (CCT), cup-to-disc ratio (CDR), disc size (DS), cup size (CS), corneal hysteresis (CH), retinal nerve fiber layer thickness (RNFLT), cup shape (CSH), and peripapillary atrophy (PPA).
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Nigus Gebremedhin Asefa, Anna Neustaeter, Nomdo M. Jansonius, Harold Snieder Tags: Genetics in Ophthalmology Source Type: research