Preconditioning of adipose ‐derived stem cells by phosphodiesterase‐5 inhibition enhances therapeutic efficacy against diabetes‐induced erectile dysfunction

ConclusionsAdipose ‐derived stem cell therapy could serve as an alternate approach for diabetes‐induced erectile dysfunction, albeit with a long onset period.In vitro preconditioning of adipose ‐derived stem cells could accelerate the functional and structural recoveryin vivo, indicating that preconditioning by inhibition of phosphodiesterase type 5 may improve adipose ‐derived stem cells therapy following diabetes‐induced erectile dysfunction.

Source: Andrology - June 18, 2019 Category: Urology & Nephrology Authors: J. Yang, Z. Yu, Y. Zhang, G. ‐H. Zang, L. Zhuan, Z. Tang, Y. Liu, T. Wang, S.‐G. Wang, J.‐H. Liu Tags: Original Article Source Type: research