Ten-year trend in prevalence and outcome of Down syndrome with congenital heart disease in a middle-income country

Conclusion: The prevalence of CHD in patients with Down syndrome is similar between Malaysia and high-income countries. The lower survival rate is attributed to limited expertise and resources which limit timely surgery.What is Known:•The survival of patients with Down syndrome with congenital heart disease (CHD) has improved in high-income countries. However, little is known about the survival of patients with Down syndrome with CHD from middle-income countries.•In the Caucasian population, atrioventricular septal defect is the most common type of CHD associated with Down syndrome.What is New:•In middle-income countries, the prevalence of CHD is the same as in high-income countries, but with a lower survival rate.•In the Asian population, ventricular septal defect is the most common type of CHD in patients with Down syndrome.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research

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ConclusionsPatients with CMS were more likely to present with increased comorbidities. Patients with CMS undergoing CABG were at risk for worse short ‐term secondary postoperative outcomes and reduced long‐term survival. The data supports the need for further investigation for risk reduction surrounding operative revascularization.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
Conclusion: the moments of discussion favored by this study served as learning to continue the future implementation of the strategies pointed out by the group and thus increasingly improve the care provided to patients with heart disease and their families.RESUMEN Objetivo: identificar, junto con el equipo de enfermer ía, estrategias para promover la seguridad del paciente en tratamiento con warfarina. Método: investigación exploratoria y descriptiva con enfoque cualitativo, realizada en las unidades de internación clínica/quirúrgica de un hospital público de referencia en ...
Source: Texto e Contexto - Enfermagem - Category: International Medicine & Public Health Source Type: research
Condition:   Coronary Artery Disease Interventions:   Diagnostic Test: CT angiography;   Diagnostic Test: Invasive coronary angiography Sponsors:   Johns Hopkins University;   Canon Medical Systems Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Chronic Thromboembolic Pulmonary Hypertension Interventions:   Drug: Macitentan;   Drug: Placebo Sponsor:   Actelion Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   2019-nCoV Intervention:   Sponsor:   Chongqing Medical University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractCardiac troponin I (cTnI) is a regulatory protein with a high sensitivity and specificity for cardiac injury. Preoperative and postoperative elevations of cTnI are usually considered predictors of the mortality and morbidity. However, little is known about the relationship between the cTnI and postoperative course after the congenital heart disease (CHD) operation. Sixty-five consecutive patients who underwent cardiac surgery for CHD at our institution between March 2016 and January 2017 were included. The cTnI was measured after the operation. Also, the association between the cTnI and duration of the catecholamin...
Source: Heart and Vessels - Category: Cardiology Source Type: research
This study examined the effect on PRU in Japanese coronary heart disease patients with long-term DAPT (aspirin  + clopidogrel) when switching from clopidogrel to prasugrel. Ninety-six patients were enrolled in this study. The median DAPT duration at enrollment was 1824.0 days. Twenty-three patients with PRU ≥ 208 at enrollment were randomly assigned into either continuing to receive clopidogrel (C ontinued Group;n = 11) or switching to prasugrel (Switched Group;n = 12). The primary endpoint was the rate of patients who achieved PRU 
Source: Heart and Vessels - Category: Cardiology Source Type: research
A passenger on a cruise ship that was denied entry from several countries amid concerns about the spread of a deadly coronavirus was confirmed to be infected with the novel coronavirus after she and her husband disembarked when the ship was allowed to dock in Cambodia. The confirmation of an infection on the ship has raised concerns about the virus’ further spread, and authorities are scrambling to confirm if other passengers might be infected, potentially spreading the virus to countries it has not yet reached. The 83-year-old American woman, who had been on board the Holland America Line ship the Westerdam, was s...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 onetime overnight Travel Source Type: news
Amid assurances that the Westerdam was disease free, hundreds of people disembarked in Cambodia and headed for airports. One was later found to be infected.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Coronavirus (2019-nCoV) Cambodia Malaysia Epidemics Sihanoukville (Cambodia) Source Type: news
(American Heart Association) Post-menopausal Hispanic women sat an average of about 8-1/2 hours per day, compared to more than 9 hours per day for non-Hispanic women.In the total sample of older women, prolonged sitting time patterns were associated with significantly greater body mass index, waist circumference, fasting blood sugar, insulin, triglycerides and insulin resistance.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
More News: Atrioventricular Septal Defect | Cardiology | Down's Syndrome | Heart | Heart Disease | Hole in the Heart | Hypertension | Malaysia Health | Pediatrics | Pulmonary Hypertension | Study | Ventricular Septal Defect