AHA News: This Faulty Gene May Help Predict Heart Muscle Disease

THURSDAY, June 20, 2019 (American Heart Association News) -- The diagnosis of a serious heart condition known as dilated cardiomyopathy often can lead doctors to run genetic tests that help determine whether the disease stems from a faulty...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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AbstractHypocalcaemic cardiomyopathy is a rare form of dilated cardiomyopathy. The authors here present two cases in which symptomatic dilated cardiomyopathy was the result of severe hypocalcaemia. First, we report about a 26 ‐year‐old woman with primary hypoparathyroidism and then about a 74‐year‐old man with secondary hypoparathyroidism following a thyroidectomy. In both cases, the left ventricular systolic function improved after calcium supplementation. In the first case, a lack of compliance led to a repeate d decrease of both serum calcium level and left ventricular systolic function. The authors also present...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Review Source Type: research
We describe various clinical settings where the appropriate use and interpretation of the ECG can provide invaluable clues, co ntributing to the important role of this basic tool as cardiovascular medicine evolves.
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Review Source Type: research
AbstractBackground Left ventricular contraction dyssynchrony (LVCD) has been related to induced ischemia and transmural scar but the interplay of myocardial viability and dyssynchrony is unknown. The aim of the present study was to establish the role of dyssynchrony in the context of a viability study performed with nitrate augmentation gated single photon emission computed tomography (GSPECT) myocardial perfusion imaging (MPI).Methods Fifty-four consecutive patients with ischemic dilated cardiomyopathy (IDC) and depressed left ventricular ejection fraction (LVEF) were included. They underwent a two-day rest/nitroglyce...
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
Publication date: Available online 30 March 2020Source: Redox BiologyAuthor(s): Cheng Zeng, Fengqi Duan, Jia Hu, Bin Luo, Binlong Huang, Xiaoying Lou, Xiuting Sun, Hongyu Li, Xuanhong Zhang, Shengli Yin, Hongmei Tan
Source: Redox Biology - Category: Biology Source Type: research
Functional mitral regurgitation (FMR) in non-ischemic cardiomyopathy (NICM) may be partly related to the dysfunction of subvalvular apparatus. Thus, we sought to investigate the correlation between papillary muscle viability and FMR changes in NICM.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (569) Source Type: research
Patients with dilated cardiomyopathy (DCM) who achieved left ventricular reverse remodeling (LVRR) have a favorable prognosis, but it is still difficult to precisely predict LVRR in the clinical setting.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (27) Source Type: research
The underlying mechanisms of right ventricular (RV) dysfunction in patients with non-ischemic dilated cardiomyopathy (NICM) remain poorly defined. We evaluated a potential correlation between local mechanical dyssynhcrony of interventricular septum (IVS) and RV function in these patients.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (568) Source Type: research
Abstract The management of dilated cardiomyopathy (DCM) is well established. However, a subset of patients does not have recovery from or have recurrences of left ventricular (LV) dysfunction despite receiving optimal medical therapy. Coronary microvascular dysfunction (CMD) can result from structural and functional abnormalities at the intramural and small coronary vessel level affecting coronary blood flow autoregulation and consequently leading to impaired coronary flow reserve. Dilated myocardial phenotype may be responsible for CMD in DCM. Anisodamine can exert a significant effect on relieving microvascular ...
Source: Journal of Traditional Chinese Medicine - Category: Complementary Medicine Authors: Tags: J Tradit Chin Med Source Type: research
We reported the effect of CF VAD in small children with dilated cardiomyopathy refractory to conventional pharmacological treatment.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (530) Source Type: research
Danon Disease (DD) is a rare X-linked disorder due to mutations in the Lysosomal Associated Membrane Protein 2 (LAMP-2) gene. Patients present with cardiac manifestations of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM). The goal of this study is to characterize the longitudinal progression of hypertrophic phenotypes and descriptions of left ventricular strain in DD.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (363) Source Type: research
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