Novel anti-obesity effect of scutellarein and potential underlying mechanism of actions

ConclusionsThese results suggest that Sc possesses important novel anti-obesity effects accompanying lipid lowering and anti-inflammation-based liver protective effects. These favorable effects are causally associated with the suppression of gene expression of inflammatory cytokines and fine regulation of genes responsible for energy metabolism. Our results advance the understanding of the pharmacological actions of Sc, and provides a role for Sc in effective management of obesity.Graphical Abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research