Nanocomposite foams based on flexible biobased thermoplastic polyurethane and ZnO nanoparticles as potential wound dressing materials

Publication date: November 2019Source: Materials Science and Engineering: C, Volume 104Author(s): Aleksandra Bužarovska, Sorina Dinescu, Andreea D. Lazar, Mirela Serban, Gratiela G. Pircalabioru, Marieta Costache, Chiara Gualandi, Luc AvérousAbstractIn the present study biobased and soft thermoplastic polyurethane (TPU), obtained by polymerization from fatty acids, was used to produce TPU/ZnO nanocomposite foams by thermally induced phase separation method (TIPS). The produced foams were characterized and evaluated regarding their potential uses as wound dressing materials. The structure and morphology of the prepared flexible polymer foams with different content of ZnO nanofiller (1, 2, 5 and 10 wt% related to the polymer) were studied by Fourier transform infrared spectroscopy (FTIR) and Scanning electron microscopy (SEM). Highly porous nanocomposite structure made of interconnected pores with dimensions between 10 and 60 μm was created allowing water vapor transmission rate (WVTR) up to 8.9 mg/cm2·h. The TPU/ZnO foams, tested for their ability to support cells and their growth, showed highest cell proliferation for TPU nanocomposite foams with 2 and 5 wt% ZnO. Overall, the nanocomposite foams displayed a low cytotoxic potential (varied proportionally to the ZnO content) and good biocompatibility. All tested nanocomposite foams were found to be significantly active against biofilms formed by different Gram-positive (Enterococcus faecalis and Staphy...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research

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Rossella Grande Surgical site infections (SSIs) represent the most common nosocomial infections, and surgical sutures are optimal surfaces for bacterial adhesion and biofilm formation. Staphylococcus spp., Enterococcus spp., and Escherichia coli are the most commonly isolated microorganisms. The aim of this research was to evaluate the antibiofilm activity of a medical device (MD) containing TIAB, which is a silver-nanotech patented product. The antibacterial effect was evaluated against Staphylococcus aureus ATCC 29213, Enterococcus faecalis ATCC 29212, and E. coli ATCC 25922 by assessing the minimum inhibitory conc...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Publication date: November 2019Source: Materials Science and Engineering: C, Volume 104Author(s): Roberta Ferreti Bonan, Mariaugusta Ferreira Mota, Rosiane Maria da Costa Farias, Sabrina Daniela da Silva, Paulo Rogério Ferreti Bonan, Luciana Diesel, Romualdo Rodrigues Menezes, Danyel Elias da Cruz PerezAbstractNanosilver immobilized on TiO2 nanometric fibers (Ag/TiO2) was produced by solution blow spinning and characterized using scanning electron microscopy, transmission electron microscopy, N2 adsorption/desorption, X-ray diffraction, X-ray photoelectron spectroscopy, water contact angle, and inductively coupled p...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
We reported the fabrication of bismuth-doped copper aluminate nanocomposites (BiCuAl2O4 NCs) via microwave-assisted method for antioxidant and antibacterial performances. As-fabricated material was characterized by electron spectroscopy techniques like X-ray diffraction (XRD), Fourier transform infrared (FTIR), energy dispersive spectroscopy (EDS), diffuse reflectance spectroscopy (DRS), X-ray photoelectron spectroscopy (XPS), Raman, scanning electron microscopy (SEM) and BET. The structural and chemical state authentication of material was confirmed by XRD, FTIR, EDS, Raman and XPS, while morphology explored by SEM. The s...
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
In conclusion, potential biological applications of PF-SeNPs were explored by antibacterial, antifungal, antioxidant and biocompatibility assays. Materials and Methods Chemicals and Reagents Sodium selenite (98%), 2,2-diphenyl-1-picrylhydrazyl (DPPH), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) (MTT), Tween 80, methanol, acetate buffer, tetracycline, nystatin, rhodamine 123, caspase-3 kit, Dulbecco’s modified Eagle media (DMEM), Folin-Ciocalteu reagent, 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS), Dulbecco’s phosphate buffered saline pH 7.4 (DPBS) and fetal bovine serum (FBS) w...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion Genomic analyses herein performed allowed us to confirm the recently (Pérez-Cataluña et al., 2018a,b) suggested amendment of A. butzleri as Al. butzlerii, comb. nov. Antimicrobial susceptibility tests defined Ab 55 and Ab 6V strains as resistant to vancomycin, tetracyclin, nalidixic acid (only Ab 55 whereas Ab 6V is intermediate resistant), erythromycin, and β-lactam antibiotics. Moreover, in our strains isolated from shellfish, we identified numerous virulence, antibiotic, and heavy metal resistance determinants, also additional to those previously found in the genome sequenced A. butzleri ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Authors: Nindawat S, Agrawal V Abstract The present study reports the biosynthesis of silver nanoparticles using aqueous root extract of Arnebia hispidissima. They were prepared by adding 10 mL root extract in 90 mL silver nitrate (0.5 mM) solution and heating at 60 ± 2 °C for 12 min at pH 7.5. Characterization of the biosynthesized silver nanoparticles was done using UV-Visible spectroscopy, field emission scanning electron microscopy, energy dispersive X-ray analysis, transmission electron microscopy, X-ray diffraction analysis, dynamic light scattering ...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Abstract We used a green sol-gel synthesis method to fabricate a novel nanoporous copper aluminosilicate (CAS) material. Nanoporous CAS was characterized using X-ray powder diffraction (XRD), field emission transmission and scanning electron microscopies (FE-TEM/FE-SEM), Fourier transform infrared (FTIR) spectroscopy, and optical analyses. The CAS was also evaluated for use as a promising disinfectant for the inactivation of waterborne pathogens. The antimicrobial action and minimum inhibitory concentration (MIC) of this CAS disinfectant were determined against eight microorganisms (Escherichia coli, Salmonella en...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Tags: Environ Sci Pollut Res Int Source Type: research
athasivam Antibiotic resistance is one of the most important global problems currently confronting the world. Different biomedical applications of silver nanoparticles (AgNPs) have indicated them to be promising antimicrobial agents. In the present study, extracellular extract of an endophytic bacterium, Pantoea ananatis, was used for synthesis of AgNPs. The synthesized AgNPs were characterized by UV–Vis spectroscopy, FTIR, transmission electron microscopy (TEM), scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDX), and Zeta potential. The antimicrobial potential of the AgNPs against pa...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
This study, the largest series of infection in MDS patients, seeks to comprehensively analyse infection in this cohort.Method: CT scan, microbiology results and hospital admission ICD codes from January 1999 to April 2017 were analysed for 657 MDS patients enrolled in the South Australian MDS (SA-MDS) registry. Cox regression analysis was performed to ascertain risk factors for developing infection.Results: There were 531 primary and 126 therapy-related myeloid neoplasm (t-MN) patients with median age of 69.2 (18-97) years. According to Revised International Prognostic Scoring System (IPSS-R), 44.7% of patients were classi...
Source: Blood - Category: Hematology Authors: Tags: 637. Myelodysplastic Syndromes-Clinical Studies: Poster I Source Type: research
Publication date: January 2019Source: Journal of Trace Elements in Medicine and Biology, Volume 51Author(s): Ravichandran Rekha, Baskaralingam Vaseeharan, Sekar Vijayakumar, Muthukumar Abinaya, Marimuthu Govindarajan, Naiyf S. Alharbi, Shine Kadaikunnan, Jamal M. Khaled, Mohammed N. Al-anbrAbstractHerein, we reported a method to synthesize selenium nanowires (Cr-SeNWs) relying to purified cysteine-rich antimicrobial peptide crustin in presence of ascorbic acid. Cr-SeNWs were characterized by UV–vis, XRD, FTIR and Raman spectroscopy, as well as SEM, HR-TEM and EDAX. The UV–vis spectroscopy peak was noted at 350&...
Source: Journal of Trace Elements in Medicine and Biology - Category: Biochemistry Source Type: research
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