An Argument for Vitamin D, A, and Zinc Monitoring in Cirrhosis.

An Argument for Vitamin D, A, and Zinc Monitoring in Cirrhosis. Ann Hepatol. 2018 Nov - Dec;17(6):920-932 Authors: Koop AH, Mousa OY, Pham LE, Corral-Hurtado JE, Pungpapong S, Keaveny AP Abstract Malnutrition is prevalent in cirrhosis. Vitamin and mineral deficiencies, including vitamin D, vitamin A, and zinc, are common and have been shown to correlate with survival. Our aim was to review the mechanisms of vitamin D, vitamin A, and zinc deficiencies in cirrhosis and the clinical assessment of affected patients, their outcomes based on the current literature, and management. This is a narrative review including the relevant literature for cirrhosis and vitamin D, vitamin A, and zinc deficiencies. Vitamin D deficiency has important effects in cirrhosis, regardless of the cause of chronic liver disease.These effects include associations with fibrosis and outcomes such as infections, hepatocellular carcinoma, and mortality. Vitamin A deficiency is associated with liver disease progression to cirrhosis and clinical decompensation, including occurrence of ascites or hepatic encephalopathy. Zinc deficiency can lead to hepatic encephalopathy and impaired immune function. Such deficiencies correlate with patient survival and disease severity. Caution should be applied when replacing vitamin D, vitamin A, and zinc to avoid toxicity. Identification and appropriate treatment of vitamin and mineral deficiencies in cirrhosis may reduce specific nutritional and cirrhos...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research

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ConclusionThe incidence of midline and lateral port site recurrence after laparoscopy for diagnosis or resection of ovarian cancer has not been determined. Limitation of trochar sites to the midline may reduce the extent of abdominal wall disease spread.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Publication date: Available online 19 July 2019Source: European Journal of RadiologyAuthor(s): Claire Boudinaud, Armand Abergel, Juliette Joubert-Zakeyh, Mikael Fontarensky, Bruno Pereira, Benoit Chauveau, Jean Marc Garcier, Pascal Chabrot, Louis Boyer, Benoît MagninAbstractPurposeGiven the growing prevalence of obesity and metabolic syndrome, the management of hepatic steatosis, especially its quantification, is a major issue. We assessed the quantification of liver steatosis using four different MR methods, in order to determine the one that is best correlated with the reference method which consists of histologica...
Source: European Journal of Radiology - Category: Radiology Source Type: research
Publication date: Available online 19 July 2019Source: European Journal of RadiologyAuthor(s): Wei Lu, Lianzhen Zhong, Di Dong, Mengjie Fang, Qi Dai, Shaoyi Leng, Liwen Zhang, Wei Sun, Jie Tian, Jianjun Zheng, Yinhua JinAbstractPurposeCervical lymph node (LN) metastasis of papillary thyroid carcinoma (PTC) is critical for treatment and prognosis. We explored the feasibility of using radiomics to preoperatively predict cervical LN metastasis in PTC patients.MethodTotal 221 PTC patients (training cohort: n = 154; validation cohort: n = 67; divided randomly at the ratio of 7:3) were enrolled and di...
Source: European Journal of Radiology - Category: Radiology Source Type: research
CONCLUSION: Reduced expression of MARK4 protein in OPCOS increases the associated risk of hyperlipidemia, hyperandrogenism and metabolic syndrome and thus the protein holds strong candidature as a drug target for the syndrome. PMID: 31322078 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Authors: Dikci S, Öztürk E, Fırat PG, Yılmaz T, Taşkapan MÇ, Yoloğlu S Abstract In the Original Article by Dikci et al. "The Association of Serum Vitamin D Levels with Pseudoexfoliation Glaucoma/ Syndrome" (Endocr Metab Immune Disord Drug Targets. 2019; 19(2):166-170) after publication of the article it has come to the corresponding author's attention that there were some errors in the article. In the introduction section, reference 3 should be changed as reference 2 (paragraph 1, line 4) and references 4-6 should be changed as references 3-6 (paragraph 1, lines 6,7). Reference number...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
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Authors: Koop AH, Mousa OY, Pham LE, Corral-Hurtado JE, Pungpapong S, Keaveny AP Abstract Malnutrition is prevalent in cirrhosis. Vitamin and mineral deficiencies, including vitamin D, vitamin A, and zinc, are common and have been shown to correlate with survival. Our aim was to review the mechanisms of vitamin D, vitamin A, and zinc deficiencies in cirrhosis and the clinical assessment of affected patients, their outcomes based on the current literature, and management. This is a narrative review including the relevant literature for cirrhosis and vitamin D, vitamin A, and zinc deficiencies. Vitamin D deficiency h...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Background: The aim of this study was to investigate the association between vitamin D deficiency (
Source: In Vivo - Category: Research Authors: Tags: Clinical Studies Source Type: research
Authors: Teriaky A, Mosli M, Chandok N, Al-Judaibi B, Marotta P, Qumosani K Abstract PURPOSE: To evaluate the prevalence of fat-soluble vitamin (A, D, and E) and zinc deficiency in patients with cirrhosis being assessed for liver transplantation and the correlations between vitamin deficiencies, nutritional markers, and severity of liver disease. METHODS: This is a single centre retrospective study. Serum vitamin A, D, E, and zinc levels were collected in adult patients being assessed for liver transplantation between January and July 2012. Patient and liver disease demographics, nutritional markers, Child-Pugh...
Source: Acta Gastro-Enterologica Belgica - Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research
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