Socioeconomic Status Is Associated with Risk of Above-knee Amputation After Periprosthetic Joint Infection of the Knee.

Socioeconomic Status Is Associated with Risk of Above-knee Amputation After Periprosthetic Joint Infection of the Knee. Clin Orthop Relat Res. 2019 Jul;477(7):1531-1536 Authors: Lieber AM, Kirchner GJ, Kerbel YE, Moretti VM, Vakil JJ, Brahmabhatt S Abstract BACKGROUND: Above-knee amputation (AKA) is a severe but rare complication of TKA. Recent evidence suggests there are sex and racial disparities with regard to AKA after TKA. However, whether lower socioeconomic status is associated with an increased risk of AKA after TKA has not been conclusively established. QUESTIONS/PURPOSES: (1) Is low socioeconomic status or use of public health insurance plans associated with an increased risk of AKA after periprosthetic joint infection (PJI) of the knee? (2) Is race or sex associated with an increased risk of AKA after PJI of the knee? METHODS: This cross-sectional study screened the National Inpatient Sample (NIS) between 2010 and 2014 using the International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) procedure and diagnosis codes to identify 912 AKAs (ICD 84.17) among 32,907 PJIs of the knee. The NIS is a large national database of inpatient hospitalizations frequently used by researchers to study outcomes and trends in orthopaedic procedures. The NIS was selected over other databases with more complete followup data such as the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) due...
Source: Clinical Orthopaedics and Related Research - Category: Orthopaedics Authors: Tags: Clin Orthop Relat Res Source Type: research

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Source: Ultrasonic Imaging - Category: Radiology Tags: Ultrason Imaging Source Type: research
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Buerger's disease (BD), or thromboangiitis obliterans, is an inflammatory, occlusive, peripheral vascular disease which usually occurs in young male smokers from low- or middle-income countries. The occlusion of small and medium-sized arteries may lead to tissue or limb loss. The aetiology and pathophysiology of the disease is not well understood. Although there is a close relationship between smoking and development or prognosis of the disease, smoking on its own cannot explain the low prevalence and geographical distribution of BD [1].
Source: Thrombosis Research - Category: Hematology Authors: Tags: Letter to the Editors-in-Chief Source Type: research
To analyze the association between cardiac autonomic modulation and arterial stiffness in patients with peripheral artery disease (PAD).
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Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
This study was conducted at the Siriraj Clinical Research Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. Each volunteer was initially treated according to either the Test-Reference (TR) or the Reference-Test (RT) sequence, after which each subject was switched to the other study sequence after a two-week washout period. Pharmacokinetic analysis was performed using log-transformed ratios (test/reference) for Cmax, AUC0-tlast, AUC0-∞, Tmax, t1/2, and λZ for both cilostazol and 3,4-dehydro-cilostazol (its active metabolite) with 90% confidence interval. Physical examination, ...
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Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Publication date: August 2019Source: The Lancet Global Health, Volume 7, Issue 8Author(s): Andre Pascal Kengne, Justin Basile Echouffo-Tcheugui
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Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
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