Internal Hernias in Pregnant Females with Roux-en-Y Gastric Bypass: A Systematic Review

Bariatric surgery has become of the most effective solutions for sustained weight loss in the world [1]. Laparoscopic Roux-en-Y gastric bypass (LRYGB) is one of the most common procedures for treatment of morbid obesity. Females are more likely to undergo a bariatric procedure for weight loss. While significant and sustained weight loss is the primary advantage to bariatric surgery, other positive outcomes include improved fertility in women [2]. This improved fertility can increase the chances of pregnancy.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Review articles Source Type: research

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Authors: Silva MAFS, Dechichi P, Limirio PHJO Abstract Childhood obesity is a considerable worldwide health problem and a major risk factor for several chronic diseases. Fat rich diets result in altered serum levels of lipids, cytokines and hormonal factors, which influence skeletal acquisition and promote microstructural and mechanical behavior changes in bone, especially to bone quality and quantity. However, the possible longterm implications of high-fat diets in childhood are controversial. Despite not fully understood, multiple signaling pathways which support bone tissue homeostasis are altered under hyperlip...
Source: Pediatric Endocrinology Reviews - Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research
Authors: Plunk EC, Richards SM Abstract The epigenome of an individual can be altered by endogenous hormones, environment, age, diet, and exposure to endocrine disrupting chemicals (EDCs), and the effects of these modifications can be seen across generations. Epigenetic modifications to the genome can alter the phenotype of the individual without altering the DNA sequence itself. Epigenetic modifications include DNA methylation, histone modification, and aberrant microRNA (miRNA) expression; they begin during germ cell development and embryogenesis and continue until death. Hormone modulation occurs during the agei...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Authors: Antinozzi C, Sgrò P, Di Luigi L Abstract Among metabolic diseases, carbohydrate metabolism disorders are the most widespread. The most common glucose pathological conditions are acquired and may increase the risk of type 2 diabetes, obesity, heart diseases, stroke, and kidney insufficiency. Phosphodiesterase type 5 inhibitors (PDE5i) have long been used as an effective therapeutic option for the treatment of erectile dysfunction (ED). Different studies have demonstrated that PDE5i, by sensitizing insulin target tissues to insulin, play an important role in controlling the action of insulin and gluco...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
CONCLUSIONS: Our results demonstrate a correlation between the required dose of metformin, BMI and hyperandrogenism. The dose of metformin should be adjusted to patients' BMI in order to obtain significant results in terms of clinical, metabolic and hormonal responses. PMID: 32767342 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Conclusion In this study the transplantation of autologous fat renders good long-term results. There is a significant correlation between change of weight and fat transplant volume survival over the years. This also explains the very high increase in breast volume in some patients. Autologous fat transplantation seems to be a safe and efficient method for breast augmentation. For further statements studies with larger number of cases are necessary. PMID: 32777824 [PubMed - as supplied by publisher]
Source: Handchirurgie Mikrochirurgie Plastische Chirurgie - Category: Cosmetic Surgery Tags: Handchir Mikrochir Plast Chir Source Type: research
Internal hernias are well-recognized complications of Roux-en-Y gastric bypass (RYGB) surgery that arise in consequence of procedure induced mesenteric defects1, 2.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
ro MP PMID: 31427221 [PubMed - as supplied by publisher]
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - Category: Surgery Authors: Tags: Surg Obes Relat Dis Source Type: research
Improved fertility following a Roux-en-Y gastric bypass (RYGB) can lead to pregnancy and increase the risk of internal herniation. A developing fetus and symptoms of pregnancy can mask the diagnosis and delay intervention, leading to deleterious maternal and fetal consequences. The aim of this systematic review is to summarize the literature regarding internal hernias during pregnancy, their management, and patient outcomes. A comprehensive literature search was undertaken on PubMed and Google Scholar to identify cases of internal hernias presenting during pregnancy after RYGB.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Review article Source Type: research
Background: Management of abdominal pain in a pregnant patient with a history of Roux-en-Y gastric bypass presents unique challenges. Internal hernias are the most common cause of small bowel obstruction after LRYGBP. Internal hernia can result in closed loop obstruction, bowel necrosis, gastric perforation, and death. Presentation: A 29-year-old female 30-week pregnancy with a history of laparoscopic Roux-en-Y gastric bypass 5 years ago. She had a 24 hours of LUQ pain with vomiting. Her pain was attributed initially to UTI.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
AbstractBariatric surgery is most commonly carried out in women of childbearing age. Whilst fertility rates are improved, pregnancy following bariatric surgery poses several challenges. Whilst rates of many adverse maternal and foetal outcomes in obese women are reduced after bariatric surgery, pregnancy is best avoided for 12 –24 months to reduce the potential risk of intrauterine growth retardation. Dumping syndromes are common after bariatric surgery and can present diagnostic and therapeutic challenges in pregnancy. Early dumping occurs due to osmotic fluid shifts resulting from rapid gastrointestinal food t...
Source: Obesity Surgery - Category: Surgery Source Type: research
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