Measuring circulating complement activation products in myeloperoxidase and proteinase 3 antineutrophil cytoplasmic antibody vasculitis

ConclusionsComplement activation occurs in both MPO ‐ANCA and PR3‐ANCA vasculitis. The complement activation profile differs by disease activity and possibly ANCA serotype. Futhan reducesin vitro complement activation and provides a more accurate measurement.This article is protected by copyright. All rights reserved.

Source: Arthritis and Rheumatology - June 18, 2019 Category: Rheumatology Authors: Eveline Y. Wu, Elizabeth A. McInnis, Sonia Boyer ‐Suavet, Carmen E. Mendoza, Lydia T. Aybar, Kristin B. Kennedy, Caroline J. Poulton, Candace D. Henderson, Yichun Hu, Susan L. Hogan, Peiqi Hu, Hong Xiao, Patrick H. Nachman, J. Charles Jenne Tags: Full Length Source Type: research