Music exposure attenuates anxiety- and depression-like behaviors and increases hippocampal spine density in male rats.

Music exposure attenuates anxiety- and depression-like behaviors and increases hippocampal spine density in male rats. Behav Brain Res. 2019 Jun 15;372:112023 Authors: Papadakakis A, Sidiropoulou K, Panagis G Abstract Epidemiological and clinical studies suggest that early-life stress (ELS) may lead to the development of mental disorders in adulthood. Maternal separation (MS) is a valid animal model of ELS that produces detrimental effects on brain and behavior of experimental animals. Positive environmental stimuli have been shown to counteract the behavioral deficits of ELS and enhance neuroplasticity. Recent data indicate that music may serve as a form of environmental enrichment in experimental animals. However, the underlying mechanisms through which musical enrichment exerts its effects are poorly understood. Male Sprague-Dawley rats were submitted to a 3 h MS protocol during postnatal days (PND) 2-14, while another group was left undisturbed. Half of the animals within each group were exposed from PND 21 to PND 76 for 12 h/day to Mozart K. 448. At approximately three months of age, elevated plus maze procedure, forced swim test and social approach task were applied to test whether music exposure can mitigate the effects of MS stress on animal emotional behaviors. Moreover, we investigated the effects of these treatments on dendritic spine density in the CA1 region of hippocampus. As expected, MS rats showed decreased sociability, increased anx...
Source: Behavioural Brain Research - Category: Neurology Authors: Tags: Behav Brain Res Source Type: research

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Conclusions: Distinctive eating behavior profiles of mothers, instead of the presence of single eating behaviors, seem to be associated with specific problematic eating behaviors of children undergoing weight loss treatment. Prospective studies are essential to determine whether these profiles can predict differential weight change trajectories in pediatric obesity treatment. PMID: 32721221 [PubMed - as supplied by publisher]
Source: Childhood Obesity - Category: Eating Disorders & Weight Management Tags: Child Obes Source Type: research
Conclusion: During antenatal care, pregnant women in the study reported having a high rate of anxiety, depression, impaired functioning, and substance use. These issues can affect a woman's health and should be further addressed for specific interventions and improved quality of care. PMID: 32724823 [PubMed - as supplied by publisher]
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
iguez-Martinez Anxiety, chronical stress, and depression during pregnancy are considered to affect the offspring, presumably through placental dysregulation. We have studied the term placentae of pregnancies clinically monitored with the Beck’s Anxiety Inventory (BAI) and Edinburgh Postnatal Depression Scale (EPDS). A cutoff threshold for BAI/EPDS of 10 classed patients into an Index group (>10, n = 23) and a Control group (<10, n = 23). Cortisol concentrations in hair (HCC) were periodically monitored throughout pregnancy and delivery. Expression differences of main glucocorticoid pathway genes...
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research
Abstract Inflammatory bowel diseases (IBDs) are chronic intestinal diseases, frequently associated with comorbid psychological and cognitive deficits. These neuropsychiatric effects include anxiety, depression, and memory impairments that can be seen both during active disease and following remission and are more frequently seen in pediatric patients. The mechanism(s) through which these extra-intestinal deficits develop remain unknown and the study of these phenomenon are hampered by a lack of murine pediatric IBD models. Herein we describe microbiota-gut-brain (MGB) axis deficits following induction of colitis i...
Source: Am J Physiol Gastroi... - Category: Gastroenterology Authors: Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research
Women who take medication for anxiety, depression or other behavioral health conditions worry about whether they’ll need to discontinue use when they conceive. For years, well-intentioned care providers believed this to be the only clinically responsible solution. The reason for this was simple: because it’s considered unethical to test medication on pregnant and nursing mothers, there was no literature to provide evidence for safety.  But we’ve come a long way, and the field of perinatal psychiatry has evolved a great deal. We now have evidence that supports the safety and efficacy of certain medic...
Source: Cord Blood News - Category: Perinatology & Neonatology Authors: Tags: Cord Blood Cord Tissue Source Type: blogs
IJERPH, Vol. 17, Pages 5427: Maternal–Infant Bonding and Its Relationships with Maternal Depressive Symptoms, Stress and Anxiety in the Early Postpartum Period in a Polish Sample International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17155427 Authors: Karolina Lutkiewicz Łucja Bieleninik Mariusz Cieślak Mariola Bidzan A large body of literature indicates that there is a relationship between maternal psychological well-being and the early maternal–infant bond. However, this relationship is not fully understood, due to the different theoretical frameworks of mater...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Introduction: The article presents a protocol of a cross-sectional study of mental health of pregnant women in relation to the coronavirus disease 19 (COVID-19) pandemic. The primary aim is to compare differences in anxiety and depression scores of pregnant women between countries affected by the COVID-19 pandemic. The secondary aim is to assess demographic, economic, and social aspects affecting maternal anxiety and depression scores among pregnant women worldwide in the time of the COVID-19 pandemic. Finally, we will be able to compare differences in perception of the different aspects of the COVID-19 pandemic (social ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
Most recent studies on SARS-Cov-2 in pregnancy have focused on physical effects of the pandemic on infected mothers and the possibility of vertical transmission rather than the equally pertinent maternal mental wellbeing. There is little doubt that pregnant women express greater levels of anxiety and depression during the pandemics weeks compared to before [1] and in particular, voiced concerns about health of their family and unborn children, as well as anxiety regarding behavioural changes such as social-isolation, working remotely, transport difficulties, childcare and stockpiling (especially of food, hand sanitizers and toiletries) [2].
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Correspondence Source Type: research
Publication date: Available online 20 July 2020Source: Pharmacology Biochemistry and BehaviorAuthor(s): Jessica E. Sparling, Kheana Barbeau, Kayla Boileau, Anne T.M. Konkle
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
Authors: Türkmen H, Yalniz Dİlcen H, Özçoban FA Abstract OBJECTIVE: The aim of this study was to determine the perception of traumatic childbirth during pregnancy and the postpartum period and the postnatal mental health outcomes of traumatic childbirth perception. METHODS: This descriptive-longitudinal study was conducted from December 2017 to June 2018 in Turkey. The study included 248 pregnant women who were in weeks 36-40 of their pregnancies. The pregnant women were administered the Scale of Traumatic Childbirth Perception(STCP) and the Health Anxiety Inventory. The women were administere...
Source: Journal of Reproductive and Infant Psychology - Category: Psychiatry & Psychology Tags: J Reprod Infant Psychol Source Type: research
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