Association between Platelet Parameters and Glaucoma Severity in Primary Open-Angle Glaucoma.

Association between Platelet Parameters and Glaucoma Severity in Primary Open-Angle Glaucoma. J Ophthalmol. 2019;2019:3425023 Authors: Ma Y, Han J, Li S, Zhang A, Cao W, Sun X Abstract Purpose: To evaluate platelet parameters in primary open-angle glaucoma (POAG) patients and to explore the association between platelet parameters and POAG severity. Methods: A total of 402 consecutive POAG patients and 408 healthy control subjects from the Department of Ophthalmology and Visual Science, Eye and ENT Hospital, Fudan University, were consecutively recruited between January 2016 and October 2018. Detailed ophthalmological and systematic examinations were performed. Blood samples for platelet parameters, including platelet count (PLT), platelet distribution width (PDW), plateletcrit (PCT), mean platelet volume (MPV), and platelet large cell ratio (P-LCR), were analyzed using an automated hematology analyzer in the department of clinical laboratory science of the hospital. The POAG subgroups were classified according to age (
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research

Related Links:

To report the first case of a cerebral arteriovenous malformation (AVM) with ocular symptoms and review the characteristics of this case and the main point of confusion for the diagnosis of such a case.
Source: BMC Ophthalmology - Category: Opthalmology Authors: Tags: Case report Source Type: research
The effect of cataract surgery on IOP in patients with primary open-angle glaucoma (POAG) is a subject of debate. We investigated the effect of cataract surgery by phacoemulsification on intraocular pressure (...
Source: BMC Ophthalmology - Category: Opthalmology Authors: Tags: Research article Source Type: research
AbstractIntroductionThe CoQun® study is a multicenter, controlled trial aimed to evaluate the neuroprotective effects of Coqun®, an ophthalmic solution of Coenzyme q10 (CoQ10) and Vitamin E (VitE), in patients affected by primary open-angle glaucoma (POAG). Pre-clinical studies and small non-controlled clinical trials have previously shown a potential role of CoQ10 and VitE in glaucoma neuroprotection, both in vitro and in vivo.MethodsRandomized, parallel arm, multicenter, double-blind study. POAG patients with an IOP ranging from 17 to 21  mm Hg on monotherapy with a prostaglandin analogue (PGA) will be consi...
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
Conclusions: Diode laser TSCPC using the slow coagulation technique is a safe and effective technique for lowering IOP in patients with refractory glaucoma in Chinese eyes. PMID: 31284800 [PubMed - as supplied by publisher]
Source: Seminars in Ophthalmology - Category: Opthalmology Tags: Semin Ophthalmol Source Type: research
ConclusionsThe surgical technique reported here can be an option to relieve dellen-associated ocular pain due to a bleb formed after tube shunt surgery.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Publication date: Available online 10 July 2019Source: Journal of Genetics and GenomicsAuthor(s): Wenmin Sun, Xueshan Xiao, Shiqiang Li, Jiamin Ouyang, Xueqing Li, Xiaoyun Jia, Xing Liu, Qingjiong Zhang
Source: Journal of Genetics and Genomics - Category: Genetics & Stem Cells Source Type: research
Publication date: Available online 10 July 2019Source: Progress in Retinal and Eye ResearchAuthor(s): Stephanie B. Syc-Mazurek, Richard T. LibbyAbstractAxonal degeneration is an active, highly controlled process that contributes to beneficial processes, such as developmental pruning, but also to neurodegeneration. In glaucoma, ocular hypertension leads to vision loss by killing the output neurons of the retina, the retinal ganglion cells (RGC). Multiple processes have been proposed to contribute to and/or mediate axonal injury in glaucoma including: neuroinflammation, loss of neurotropic factors, dysregulation of the neuro...
Source: Progress in Retinal and Eye Research - Category: Opthalmology Source Type: research
Conditions:   Open Angle Glaucoma;   Normal Tension Glaucoma;   Healthy Intervention:   Diagnostic Test: LASER SPECKLE FLOWGRAPHY Sponsors:   University of Zurich;   Cantonal Hosptial Aarau, Department of Ophthalmology, Aarau, Switzerland Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 9 July 2019Source: Pharmacology &TherapeuticsAuthor(s): Claudio Bucolo, Gian Marco Leggio, Filippo Drago, Salvatore SalomoneAbstractDopamine (DA) and DA receptors (DR) have been extensively studied in the central nervous system (CNS), but their role in the periphery is still poorly understood. Here we summarize data on DA and DRs in the eye, cardiovascular system and endocrine pancreas, three districts where DA and DA-related drugs have been studied and the expression of DR documented. In the eye, DA modulates ciliary blood flow and aqueous production, which impacts on intraocular pre...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Conclusions: Corticosteroids, in combination with anti-infectives, could be a promising treatment option for acute conjunctivitis subject to development of further evidence on their effectiveness and safety in conjunctivitis treatment.
Source: Cornea - Category: Opthalmology Tags: Review Source Type: research
More News: Glaucoma | Hematology | Laboratory Medicine | Opthalmology | Science | Statistics