The maternal pre-pregnancy BMI and the risk of ADHD among children and adolescents: A systematic review and meta-Analysis.

The maternal pre-pregnancy BMI and the risk of ADHD among children and adolescents: A systematic review and meta-Analysis. Korean J Pediatr. 2019 Jun 14;: Authors: Jenabi E, Bashirian S, Khazaei S, Basiri Z Abstract This meta-analysis evaluated the association between maternal pre-pregnancy body mass index (BMI) and the risk of attention deficit hyperactivity disorder (ADHD) among children and adolescents. The search strategy was conducted until December 2018 in databases of PubMed, Web of Science and Scopus. The ORs or HRs with 95% confidence intervals (CI) extracted from eligible studies used as the common measure of association among studies. A significant association was found between overweight women and risk of ADHD among children with the pooled estimates of HR and OR, respectively (HR = 1.27, 95% CI = 1.17 to 1.37) and (OR = 1.28, 95% CI = 1.15 to 1.40). Also, this association was significant between obese women and risk of ADHD among children and adolescents with the pooled estimates of HR and OR, respectively (HR = 1.65, 95% CI = 1.55 to 1.76) and (OR = 1.42, 95% CI = 1.23 to 1.61). There is sufficient evidence based on the current epidemiological studies that pre-pregnancy overweight and obesity is significantly associated with an increased risk of ADHD among children and adolescents. These findings provide a new approach for prevention of ADHD by controlling weight gain in the prenatal period, which should be considered by policymakers. PM...
Source: Korean Journal of Pediatrics - Category: Pediatrics Tags: Korean J Pediatr Source Type: research

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AbstractPurpose of ReviewTo present current data on the coexistence of attention deficit hyperactivity disorder (ADHD) and the metabolic syndrome and type 2 diabetes mellitus in adults and children and to discuss possible mechanisms.Recent FindingsEmerging data suggest that risk factors for obesity and insulin resistance such as diabetes during pregnancy and intrauterine growth failure may also have a role in the development of ADHD. Furthermore, ADHD and obesity share lifestyle factors, such as abnormal eating patterns, binge eating, and a sedentary lifestyle. ADHD is a risk factor for components of the metabolic syndrome...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
Abstract The anti-inflammatory diet is based on two diets that have been shown to have many positive health effects-the Mediterranean diet and the Okinawan diet. The anti-inflammatory diet is more than just a prescription for healthy food, but rather a way of life characterized by a plant-based diet and a pattern of living that includes eating a diverse range of locally grown foods eaten in season, conviviality, culinary activities, physical activity, and rest. The Mediterranean diet has been shown to reduce the burden and even prevent the development of cardiovascular disease, breast cancer, depression, colorecta...
Source: Pediatric Annals - Category: Pediatrics Authors: Tags: Pediatr Ann Source Type: research
In this study, we explore shared epigenetic mechanisms of the association between mtDNA content and insulin levels, supporting the developmental origins of this link. First, the association between cord blood insulin and mtDNA content in 882 newborns of the ENVIRONAGE birth cohort was assessed. Cord blood mtDNA content was established via qPCR, while cord blood levels of insulin were determined using electrochemiluminescence immunoassays. Then the cord blood DNA methylome and transcriptome were determined in 179 newborns, using the human 450K methylation Illumina and Agilent Whole Human Genome 8 × 60 K microarrays, r...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
The objective of this study was to examine the relationship between pre-pregnancy maternal weight status and offspring physician visits for mental health conditions in childhood and adolescence. We conducted a population-based retrospective cohort study of singleton infants born between the years of 1989 and 1993 using a linkage of the Nova Scotia Atlee Perinatal Database with administrative health data. Offspring were followed from birth to age 18  years. Maternal weight status was categorized according to WHO body mass index cutoffs. The number of physician visits for any mental health condition, mood, anxiety, and ...
Source: European Child and Adolescent Psychiatry - Category: Psychiatry Source Type: research
What do a can of corn, a take-out pizza, a reusable water bottle, a bright green yogurt, and an inflatable pool toy have in common? They all contain food additives or chemicals that can be dangerous for children. Over the last few decades, the number of chemicals added to foods and other products has skyrocketed. We have created all sorts of plastics that are used in innumerable ways. We add preservatives to foods to keep them fresh. We add chemicals to foods to make them look more appealing. We have made food packaging to keep food fresh. We add chemicals to lotions and beauty products to make them feel, look, and sm...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Children's Health Environmental health Parenting Source Type: blogs
Location:College of Medicine, Veterinary and Life Sciences, Glasgow, United KingdomSalary:A stipend of£14,553& tuition feesClosing Date:10 January 2018 Supervisors: Dr Michelle Bellingham, Dr Amanda Drake, Prof Paul A. FowlerProject details: The fetal environment plays a key role in programming normal brain development in the womb. Maternal lifestyle factors such as malnutrition, obesity, smoking and alcohol consumption are associated with altered brain development and behaviour, including attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD) and anxiety disorders in the o...
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Conclusion: Prenatal and early postnatal exposures to p,p′-DDE and PCB-153 were associated with a higher prevalence of abnormal scores for conduct and hyperactivity at 5–9 y of age in our study population. These findings provide further support for the importance of minimizing organochlorine exposures to young children and to women of childbearing age. https://doi.org/10.1289/EHP553 Received: 24 May 2016 Revised: 29 August 2017 Accepted: 29 August 2017 Published: 03 October 2017 Address correspondence to A.H. Rosenquist, Department of Clinical Epidemiology, Olof Palmes Allé 43-45, 8200 Aarhus N, De...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Conclusion: Prenatal and early postnatal exposures to p,p′-DDE and PCB-153 were associated with a higher prevalence of abnormal scores for conduct and hyperactivity at 5–9 y of age in our study population. These findings provide further support for the importance of minimizing organochlorine exposures to young children and to women of childbearing age. https://doi.org/10.1289/EHP553 Received: 24 May 2016 Revised: 29 August 2017 Accepted: 29 August 2017 Published: 03 October 2017 Address correspondence to A.H. Rosenquist, Department of Clinical Epidemiology, Olof Palmes Allé 43-45, 8200 Aarhus N, De...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Conclusion: Exposure to residential surrounding greenness was associated with better scores on tests of attention at 4–5 y and 7 y of age in our longitudinal cohort. https://doi.org/10.1289/EHP694 Received: 23 June 2016 Revised: 20 July 2017 Accepted: 21 July 2017 Published: 18 September 2017 Address correspondence to P. Dadvand, ISGlobal, Doctor Aiguader, 88, 08003, Barcelona, Spain. Telephone: 34 93 214 7317. Email: payam.dadvand@isglobal.org Supplemental Material is available online (https://doi.org/10.1289/EHP694). The authors declare they have no actual or potential competing financial interests. Note to r...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
AbstractThe risk of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) may be influenced by environmental factors such as maternal obesity before pregnancy. Previous studies investigating those associations have found divergent results. We aim to investigate in a large birth cohort this association further in children with ADHD, ASD and comorbid ADHD and ASD. Our study population consisted of 81,892 mother –child pairs participating in the Danish National Birth Cohort (DNBC). Information about pre-pregnancy weight and height was collected in week 16 of pregnancy; the analysis was divi...
Source: European Child and Adolescent Psychiatry - Category: Psychiatry Source Type: research
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