[ASAP] Familial L723P Mutation Can Shift the Distribution between the Alternative APP Transmembrane Domain Cleavage Cascades by Local Unfolding of the ?-Cleavage Site Suggesting a Straightforward Mechanism of Alzheimer ’s Disease Pathogenesis

ACS Chemical BiologyDOI: 10.1021/acschembio.9b00309

Source: ACS Chemical Biology - June 19, 2019 Category: Chemistry Authors: Eduard V. Bocharov* †‡, Kirill D. Nadezhdin†‡, Anatoly S. Urban†‡, Pavel E. Volynsky†, Konstantin V. Pavlov§, Roman G. Efremov†‡?, Alexander S. Arseniev†‡, and Olga V. Bocharova†‡ Source Type: research