Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.

CONCLUSIONS Despite increased statistical power accorded by meta-analysis, the authors identified no reliable predictors of antidepressant treatment outcome, although they did identify modest, direct evidence that common genetic variation contributes to individual differences in antidepressant response. PMID: 23377640 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/PubMed/23377640?dopt=Abstract

Source: The American Journal of Psychiatry - February 1, 2013 Category: Psychiatry Authors: GENDEP Investigators, MARS Investigators, STAR*D Investigators Tags: Am J Psychiatry Source Type: research