Added Value of Contrast Medium in Whole-Body Hybrid PET/MRI: Comparison Between Contrast-Enhanced and Non-Contrast-Enhanced Protocols

Objective: To compare the diagnostic ability and time efficiency of contrast-enhanced (CE) whole body FDG PET/MRI protocol and non-contrast-enhanced (NCE) protocol. Subjects and Methods: Ninety-three patients with known primary tumors underwent whole-body hybrid FDG PET/MRI during the follow-up of their malignancies with the use of NCE and CE protocols. The NCE PET/MRI protocol consisted of diffusion-weighted (b = 0 s/mm2 and 800 s/mm2) and T1-weighted Turbo Flash in the axial plane and T2-weighted HASTE sequence in the coronal planes ( ∑ = 25 minutes). The CE PET/MRI protocol was performed by acquiring axial serial CE 3D FS VIBE images in the upper abdomen, completing the whole body in late phase in the axial plane (∑ = 30 minutes). Results: There was a statistically significant difference between the total number of lesions detected by the CE protocol (median 2, IQR 0-14) and that detected by the NCE protocol (median 1, IQR 0-5) (p
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research