Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis.

Sepsis is a heterogeneous syndrome. Identification of distinct clinical phenotypes may allow more precise therapy and improve care. In this retrospective analysis of data sets from patients with sepsis, 4 clinical phenotypes were identified that correlated with host-response patterns and clinical outcomes, and simulations suggested these phenotypes may help in understanding heterogeneity of treatment effects. Further research is needed to determine the utility of these phenotypes in clinical care and for informing trial design and interpretation.

Source: Current Awareness Service for Health (CASH) - June 19, 2019 Category: Consumer Health News Source Type: news