New Serotoninergic Ligands Containing Indolic and Methyl Indolic Nuclei: Synthesis and in Vitro Pharmacological Evaluation.

CONCLUSION: Compounds 7f and 10a showed a nanomolar affinity towards 5-HT1A with an in vitro pharmacologic profile compatible with antipsychotic drugs.
PMID: 31203804 [PubMed - as supplied by publisher]

Source: Medicinal Chemistry - June 12, 2019 Category: Chemistry Authors: Magli E, Severino B, Corvino A, Perissutti E, Frecentese F, Saccone I, Giordano F, Castro M, Brea J, Loza MI, Santagada V, Caliendo G, Fiorino F Tags: Med Chem Source Type: research