Procedural Pause: Golden Rules for Lumbar Puncture, Video 1
James R. Roberts, MD, &Martha Roberts, CEN, ACNP, wrap up their lumbar puncture series with some pearls for LP patients. Read the blog post, “Lumbar Puncture: Golden Rules” at http://bit.ly/ProceduralPause, and then watch how to set up a sterile field in this video.
This study aims to evaluate evidence for construct and content validity of 4 interchangeable lumbar puncture (LP) complex anatomic configurations of this simulator. We performed a cross-sectional study between April 2018 and May 2019. Novice volunteer medical students and expert physicians who had performed over 30 LP procedures performed sequential LP procedures on each of 4 simulated interchangeable anatomic LP puncture blocks (normal, obesity, geriatric, combined geriatric/obesity). Primary outcome measures compared between groups for each LP procedure were return of cerebrospinal fluid within 5 minutes and a calculate...
CONCLUSION: Educational intervention with serial album was effective and contributed to immobility and positioning of pregnant women. Brazilian Registry of Clinical Trials (RBR-3Z7SRD). PMID: 33027488 [PubMed - as supplied by publisher]
Conclusion: In people living with HIV with neurological/neurocognitive symptoms, peripherally effective dual therapy can show CSF virosuppression, inflammation, neuronal and astrocyte integrity and neurocognition comparable to triple therapy.
A 13-year-old boy reported acute horizontal binocular diplopia and headache. Ten days prior to these symptoms, he suffered from a gastrointestinal infection. Ophthalmological examination revealed bilateral ophthalmoparesis and diffuse hyporeflexia. Magnetic resonance imaging of the brain was normal. Lumbar puncture revealed albumin-cytological dissociation. There were no anti-GQ1b antibodies, but serum anti-GM1 antibodies were raised. He received intravenous immunoglobulins and had fully recovered two weeks later.
CONCLUSIONS: Currently, the LP procedure in the neonatal period is mainly performed with a trocar needle with a stylet and with the widespread use of different analgesic measures. PMID: 32998845 [PubMed - as supplied by publisher]
No abstract available
PMID: 32978805 [PubMed - as supplied by publisher]
Conclusion: It is a diagnostic challenge when recurrent branch retinal artery occlusion secondary to Susac syndrome presents without the classic symptoms. Optical coherence tomography angiography and subtle magnetic resonance imaging findings aided in early recognition of the diagnosis in our patient. Ultra-wide-field fluorescein angiography was an important tool in disease monitoring. Aggressive management with intravenous corticosteroids and initiation of immunosuppression resulted in long-term preservation of vision and improvement in visual field.
CONCLUSIONS: Results suggest that the pathophysiology of depression in PWH differs from that in HIV- individuals. Specifically, lower central dopaminergic activity was selectively associated with greater depressive symptoms and neuroinflammation in PWH. With the rise in consideration of DA agonists for the treatment of depression, these results suggest that PWH may show a greater response to these agents than their HIV- peers. PMID: 32966871 [PubMed - as supplied by publisher]
The Dorsal Column of this issue ofBrain features a perspective by Bart Lutters and Peter Koehler that looks back at the history of cisterna magna puncture, a procedure that was first described in detail by James Bourne Ayer in 1920. They point out that adoption of the technique was driven, to a great extent, by the goal of delivering therapeutic agents directly to the CNS, and that its popularity waned as antibiotics that could be administered intramuscularly or intravenously replaced intrathecal anti-meningococcal serum, arsphenamine and ‘salvarsanized’ serum (a cocktail of arsphenamine and the patient’s...