Efficacy of surgical excision and sub-dermal injection of triamcinolone acetonide for treatment of keloid scars after caesarean section: a single blind randomised controlled trial protocol

DiscussionWe anticipate that surgical excision and steroid injection will be a safe, lasting and cost-effective treatment in the management of caesarean keloid scars which will be useful for patients unable to undergo cosmetic surgery due to clinical or financial reasons.Trial registrationAustralian New Zealand Clinical Trials Registry,ACTRN12618000984291. Registered on 12 June 2018.
Source: Trials - Category: Research Source Type: clinical trials

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One of the first-line options to treat keloid scars is corticosteroid injection after excision of the existing scar. A thorough literature search has shown a lack of research on the injection of corticosteroid...
Source: Trials - Category: General Medicine Authors: Tags: Study protocol Source Type: research
ConclusionThis case highlights one of the more serious complications of circumcision. Although penile keloids are rare, the techniques involved in traditional circumcision potentially predispose to keloid formation in a genetically prone population.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
CONCLUSION Combination keloid therapy using fractional lasers, superficial cryotherapy, and intralesional triamcinolone injection is safe and more effective than individual monotherapies.
Source: Dermatologic Surgery - Category: Dermatology Tags: Original Article Source Type: research
Autologous fat grafting is a technique with various applications in the craniofacial region ranging from the treatment of wounds, scars, keloids, and soft tissue deformities. In this review, alternative therapies to fat grafting are discussed. These are composed of established therapies like silicone gel or sheeting, corticosteroids, cryotherapy, and laser therapy. Novel applications of negative pressure wound therapy, botulinum toxin A injection, and biologic agents are also reviewed.
Source: Journal of Craniofacial Surgery - Category: Surgery Tags: Special Editorials Source Type: research
Authors: Bi M, Sun P, Li D, Dong Z, Chen Z Abstract BACKGROUND The optimal treatment for hypertrophic scar and keloid remains controversial. Therefore, the aim of this systematic review and meta-analysis was to compare the effectiveness of intralesional injection of botulinum toxin type A compared with placebo and intralesional injection of corticosteroid compared with placebo in patients with hypertrophic scar and keloid. MATERIAL AND METHODS Six databases were searched using Medical Subject Headings (MeSH) keywords and included Web of Science, PubMed, EMBASE, the Cochrane Library, WanFang, and CNKI from their inc...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research
Conditions:   Keloid;   Alopecia Areata;   Acne;   Hypertrophic Scar;   Epidermal Inclusion Cyst;   Frontal Fibrosing Alopecia;   Lichen Plano-Pilaris;   Keratoacanthoma;   Plaque Psoriasis;   Lichen Simplex Chronicus;   Prurigo Nodularis;   Nummular Eczema;   Granuloma Annulare;   M orphea;   Lichen Planus Interventions:   Drug: Corticosteroid with lidocaine;   Drug: Corticosteroid with normal saline Sponsor:   Vanderbilt Uni...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This article is protected by copyright. All rights reserved. PMID: 30101410 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
Authors: Morelli Coppola M, Salzillo R, Segreto F, Persichetti P Abstract Keloids are pathological scars presenting as nodular lesions that extend beyond the area of injury. They do not spontaneously regress, often continuing to grow over time. The abnormal wound-healing process underlying keloid formation results from the lack of control mechanisms self-regulating cell proliferation and tissue repair. Keloids may lead to cosmetic disfigurement and functional impairment and affect the quality of life. Although several treatments were reported in the literature, no universally effective therapy was found to date. Th...
Source: Clinical, Cosmetic and Investigational Dermatology - Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research
Background: Effective treatment of keloids is challenging as the recurrence rate after surgical excision is high. Earlobe keloids are unique due to the low tension in this area, their tendency to respond better to therapy, and their lower recurrence rates after excision. Combination therapy with intralesional corticosteroids is commonly utilized to maximize treatment success. Data on the best treatment practices are lacking.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
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