Rapid myelin water imaging for the assessment of cervical spinal cord myelin damage

ConclusionGRASE is sufficiently sensitive to detect decreased myelin within MS spinal cord plaques, NMO lesions, and PLS diffuse spinal cord injury. Decreased MWF in PLS is consistent with demyelination secondary to motor neuron degeneration. GRASE MWI is a feasible method for rapid assessment of myelin content in the cervical spinal cord and provides complementary information to that from DTI and qT1 measures.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research