Are Modest Gains From Two-Stent Glaucoma Surgery Worth Pursuing? Are Modest Gains From Two-Stent Glaucoma Surgery Worth Pursuing?

It may not replace trabeculectomy yet, but there is value associated with this second-generation microinvasive surgery.Medscape Ophthalmology
Source: Medscape Ophthalmology Headlines - Category: Opthalmology Tags: Ophthalmology Viewpoint Source Type: news

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AbstractPurpose of ReviewMarijuana has been known to decrease intraocular pressure in humans since the early 1970s. However, its broad side effect profile, short half-life, and limited corneal penetration have prevented its development into a commercial ocular anti-hypertensive. Our paper aims to evaluate the latest research on the role of cannabinoids in the treatment of glaucoma and whether or not there is any progress in overcoming the above limitations.Recent FindingsSeveral techniques for retaining the therapeutic effect and minimizing or eliminating the side effects of Δ-9-tetrahydrocannabinol are being investi...
Source: Current Ophthalmology Reports - Category: Opthalmology Source Type: research
Conclusion: The present study highlights that patients with long-term glaucoma medications need to be assessed for LLT parameters objectively evaluate their ocular surface health.
Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
Conclusion: AADI implantation in PS or AC is a safe and effective method for IOP control in refractory glaucoma with its low cost being of significance in developing countries.
Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
Parthopratim Dutta Majumder, Jayshree, Rathini Lilian David, Viswanath KaushikIndian Journal of Ophthalmology 2019 67(8):1360-1362 A 52-year-old woman presented with idiopathic active scleritis not responding to oral cyclophosphamide, azathioprine, and oral steroid. Her intraocular pressure in the left eye was 45 mm of Hg in spite of using combination of brinzolamide 1% and brimonidine 0.2% (thrice a day), timolol maleate 0.5% (twice a day) eye drops in both eyes and oral acetazolamide. She was administered subcutaneous golimumab 50 mg injection every 4 weeks along with oral methotrexate 15 mg/week. The sclera...
Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
All‑trans‑retinoic acid modulates TGF‑β‑induced apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting PI3K/AKT signaling. Mol Med Rep. 2019 Jul 18;: Authors: Liang L, Wang X, Zheng Y, Liu Y Abstract Conjunctival fiber generation is implicated in a wide spectrum of ocular diseases. Conjunctival wound healing is characterized by inflammation followed by re‑epithelialization, synthesis of new extracellular matrix (ECM), wound contraction and subconjunctival scar formation. The primary cause for the failure of glaucoma filtration sur...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Conclusions: At MTW, glaucoma potentially plays a part in around one in eight falls resulting in hospital admission, at considerable personal and financial cost. We suggest that further work should explore early diagnosis of glaucoma, treatment and mitigation of falls risk. PMID: 31322025 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - Category: Health Management Tags: J Med Econ Source Type: research
Conclusions: The studied polymorphic variants of ESR1 and ESR2 genes may have an influence on the clinical phenotype of patients with POAG. PMID: 31322012 [PubMed - as supplied by publisher]
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
Authors: Dikci S, Öztürk E, Fırat PG, Yılmaz T, Taşkapan MÇ, Yoloğlu S Abstract In the Original Article by Dikci et al. "The Association of Serum Vitamin D Levels with Pseudoexfoliation Glaucoma/ Syndrome" (Endocr Metab Immune Disord Drug Targets. 2019; 19(2):166-170) after publication of the article it has come to the corresponding author's attention that there were some errors in the article. In the introduction section, reference 3 should be changed as reference 2 (paragraph 1, line 4) and references 4-6 should be changed as references 3-6 (paragraph 1, lines 6,7). Reference number...
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Authors: Shubhakaran K PMID: 31315344 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusion: The expression of sFRP1 accelerates the aging process in mouse eyes and future studies are warranted to elucidate the underlying mechanisms. PMID: 31318361 [PubMed]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
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