Gestational Diabetes Mellitus

Although it has been accepted for decades that women with gestational diabetes mellitus (GDM) are at high risk for future development of type 2 diabetes, vigorous debate regarding the value of detecting and treating GDM has persisted into the twenty-first century. Although results from 2 randomized trials provide strong evidence that treating GDM reduces adverse perinatal outcomes, it remains to be determined whether treatment impacts long-term offspring outcomes. Insulin is the first-line pharmacologic treatment and is added when glycemic goals are not met with nutritional modifications. Oral agent use is controversial, as data on long-term offspring outcomes are lacking.

Source: Endocrinology and Metabolism Clinics of North America - June 17, 2019 Category: Endocrinology Authors: Emily D. Szmuilowicz, Jami L. Josefson, Boyd E. Metzger Source Type: research