Scedosporium spp. osteomyelitis: A case report.

We present here a case of a 54- year- old male patient with a diagnosis of chronic bacterial osteomyelitis due to an aquatic accident and exposed fracture of tibia-fibula of both members, which was treated with broad-spectrum antibiotics for 120 days. Eight months after the onset of the disease, Scedosporium spp. was isolated from the collection of one of the affected member, which was treated with voriconazole in combination with terbinafine. PMID: 31204057 [PubMed - as supplied by publisher]
Source: Revista Argentina de Microbiologia - Category: Microbiology Tags: Rev Argent Microbiol Source Type: research

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Authors: George E, Rajalakshmi A Abstract Melioidosis is an infectious disease caused by gram negative bacterium Burkholderia pseudomallei. It is a soil and water pathogen and transmitted to humans through inoculation or inhalation. This disease is considered endemic in India and largely remains under reported. The most common presentation is pneumonia and bacteraemia, which can present acutely and as septic shock. Chronic presentation include-abscess, septic arthritis, osteomyelitis. The major risk factors are diabetes, liver disease, renal disease, chronic lung disease. In this article 18 cases have been reviewed...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
We present a case report of Pott’s puffy tumor with frontal sinus and epidural abscess, and review the literature with proposal of terminology change to a more accurate description as Pott’s puffy “abscess”.
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
CONCLUSIONS: The TIDOS project has focused research on four initiatives: (1) blast-related wound infection epidemiology and clinical management; (2) DoD-VA outcomes research; (3) Multidrug- Resistant and other Virulent Organisms Trauma Infections Initiative; and (4) Joint Trauma System clinical practice guidelines and antibiotic stewardship. There is a continuing need for longitudinal data platforms to support battlefield wound research and clinical practice guideline recommendation refinement, particularly to improve care for future conflicts. As such, maintaining a research platform, such as TIDOS, would negate the lengt...
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
ConclusionOral bisphosphonates appear to provide prolonged symptom relief in patients with DSO compared to previous treatment strategies, however the exact regime and length of use is still unknown. The positive impact of bisphosphonates may provide a potential insight into the pathophysiology of DSO.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
Publication date: Available online 29 November 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Marieke M. van de Meent, Miranda J.M. Wetselaar-Glas, Marta Fiocco, Natasha M. Appelman-Dijkstra, J.P.Richard van MerkesteynSummaryNon-surgical therapy has proved to be effective in chronic diffuse sclerosing osteomyelitis (DSO) of the mandible in children. Therefore we aimed to investigate the effect of non-surgical therapy in adult DSO patients.We included consecutive patients with DSO who received non-surgical therapy in our center. They all received occlusal splint therapy, counselling about the disease, and/or ...
Source: Journal of Cranio Maxillofacial Surgery - Category: ENT & OMF Source Type: research
I congratulate the authors for presenting a minimally invasive approach to pubic symphyseal debridement with or without cystectomy in patients with urosymphyseal fistulas (USFs). Although a rare complication of prostate cancer radiotherapy treatment, USF and its associated osteomyelitis frequently result in debilitating pain, sepsis, decreased quality of life, and potentially increased mortality. The traditional treatment of this difficult problem has been to perform an open pubic bone debridement with either cystectomy and ileal conduit if the bladder is not salvageable, or to perform a USF closure with rectus muscle flap...
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
Conclusion: From our study, we infer that ESBL producers and qnr gene-possessing strains are frequently resistant to ciprofloxacin. Estimation of the MPC in the case of multidrug-resistant isolates in the clinical setup may help in treating these drug-resistant strains. PMID: 31772582 [PubMed]
Source: International Journal of Microbiology - Category: Microbiology Tags: Int J Microbiol Source Type: research
Diffuse sclerosing osteomyelitis (DSO) is a poorly understood chronic inflammatory disease, for which many aetiological theories and treatment modalities have been suggested. We retrospectively evaluated bisphosphonate treatment outcomes for DSO patients with comparison to alternative treatment modalities and current literature.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Tags: Review Article Source Type: research
ConclusionOur patient ’s long-term end-stage renal disease had made the oral and gastrointestinal mucosal barriers very fragile. Under these conditions, even mildly invasive procedures such as tracheal intubation and nasogastric tube insertion could be the cause of infectious complication by oral commensals, includingActinomyces.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
ConclusionIn subjects with complicated and prolonged MRSA bacteremia requiring supplemental ceftaroline, clinical outcomes did not differ among patients prescribed vancomycin or daptomycin alone following bacteremia resolution versus patients who continued combination therapy.
Source: Infectious Diseases and Therapy - Category: Infectious Diseases Source Type: research
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