The relationship between alpha asymmetry and ADHD depends on negative affect level and parenting practices

Publication date: Available online 18 June 2019Source: Journal of Psychiatric ResearchAuthor(s): Brittany R. Alperin, Christiana J. Smith, Hanna C. Gustafsson, McKenzie T. Figuracion, Sarah L. KaralunasAbstractAtypical frontal alpha asymmetry is associated with the approach/withdrawal and affective processes implicated in many psychiatric disorders. Rightward alpha asymmetry, associated with high approach, is a putative endophenotype for attention deficit/hyperactivity disorder (ADHD). However, findings are inconsistent, likely because of a failure to consider emotional heterogeneity within the ADHD population. In addition, how this putative risk marker interacts with environmental factors known to increase symptom severity, such as parenting practices, has not been examined. The current study examined patterns of alpha asymmetry in a large sample of adolescents with and without ADHD, including the moderating role of negative affect and inconsistent discipline. Resting-state EEG was recorded from 169 well-characterized adolescents (nADHD = 79). Semi-structured clinical interviews and well-validated rating scales were used to create composites for negative affect and inconsistent discipline. The relationship between alpha asymmetry and ADHD diagnosis was moderated by negative affect. Right asymmetry was present only for those with ADHD and low levels of negative affect. In addition, greater right alpha asymmetry predicted severity of ADHD symptoms for those with the disorder, ...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research

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Conclusion Consumption showed an increase in use of methylphenidate in South Africa, with small changes observed over the study period. Further studies are required.
Source: International Journal of Clinical Pharmacy - Category: Drugs & Pharmacology Source Type: research
Condition:   Attention Deficit Hyperactivity Disorder in Adults Intervention:   Other: questionnaires Sponsor:   University Hospital, Strasbourg, France Not yet recruiting
Source: - Category: Research Source Type: clinical trials
To the Editor In their cohort study, Brander et al observed an increased risk of metabolic and cardiovascular diseases in patients with Tourette syndrome (TS) and chronic tic disorder. This risk was even higher in patients with comorbid attention-deficit/hyperactivity disorder. Interestingly, metabolic and cardiovascular risks were already present at an early stage of the disorder and were actually decreased in patients that used antipsychotic medication for a longer time. These data are relevant for the field because they were previously unknown in this form and must be considered in the future care of these patients.
Source: JAMA Neurology - Category: Neurology Source Type: research
Abstract Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder and is characterized by symptoms of inattention and/or hyperactivity and impulsivity. In the current study, we obtained quantitative EEG (QEEG) recordings of 51 children aged between 6 and 12 years before the initiation of methylphenidate treatment. The relationship between changes in the scores of ADHD symptoms and initial QEEG features (power/power ratios values) were assessed. In addition, the children were classified as responder and nonresponder according to the ratio of their response to the medication (&g...
Source: Clinical EEG and Neuroscience - Category: Neuroscience Authors: Tags: Clin EEG Neurosci Source Type: research
CONCLUSIONS: Suicidal risks were high in mood disorders: ideation was highest with BD type II, attempts and suicides (especially violent) with BD type I. Several risk factors for suicidal acts differed between BD versus MDD patients.Declaration of interestNo author or immediate family member has financial relationships with commercial entities that might appear to represent potential conflicts of interest with the information presented. PMID: 31292010 [PubMed - as supplied by publisher]
Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research
Publication date: September 2019Source: Research in Developmental Disabilities, Volume 92Author(s): Guillaume Pineau, Thomas Villemonteix, Hichem Slama, Martin Kavec, Danielle Balériaux, Thierry Metens, Simon Baijot, Alison Mary, Nicolas Ramoz, Philip Gorwood, Philippe Peigneux, Isabelle MassatAbstractDopamine active transporter gene (DAT1) is a candidate gene associated with attention-deficit/hyperactivity disorder (ADHD). The DAT1 variable number tandem repeat (VNTR)-3’ polymorphism is functional and 9R carriers have been shown to produce more DAT than 10R homozygotes. We used functional magnetic resonance i...
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
DiscussionAs psychotherapy is among the treatments of choice for most adult psychiatric disorders, a systematic review evaluating the benefits and harms of short-term compared with long-term psychotherapy is urgently needed. It is the hope that this review will be able to inform best practice in treatment and clinical research of these highly prevalent and burdensome disorders.Systematic review registrationPROSPEROCRD42019128535
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research
Methylphenidate is a stimulant drug that doctors prescribe to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. Learn about how it works, its side effects, and typical dosages here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: ADHD / ADD Source Type: news
Purpose of review To review the literature and provide a guide to assessing patients with problematic interactive media use (PIMU). Recent findings 0.3–1.0% of the world population meets criteria for internet gaming disorder (IGD). 26.8–83.3% of adolescents meeting criteria for internet addiction have comorbid attention-deficit/hyperactivity disorder. IGD is associated with increased anxiety and social anxiety/phobias. Group counseling, cognitive behavioral therapy, and sports intervention are associated with significant reductions in internet addiction. Summary With the Diagnostic and Statistical Manua...
Source: Current Opinion in Pediatrics - Category: Pediatrics Tags: ADOLESCENT MEDICINE: Edited by Sara F. Forman and Sarah Pitts Source Type: research
A large body of research has shown that exposure to community violence is common for many children across the world. However, less is known about exposure in particular subgroups such as those children with developmental disorders. To address this research...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
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