Exercise training undertaken by people within 12 months of lung resection for non-small cell lung cancer.

CONCLUSIONS: Exercise training increased exercise capacity and quadriceps muscle force of people following lung resection for NSCLC. Our findings also suggest improvements on the physical component score of general HRQoL and decreased dyspnoea. This systematic review emphasises the importance of exercise training as part of the postoperative management of people with NSCLC. PMID: 31204439 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research

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Publication date: Available online 16 July 2019Source: The Lancet Respiratory MedicineAuthor(s): Alessandro N Franciosi, Tomás P Carroll, Noel G McElvaneySummaryα1-antitrypsin deficiency (AATD) remains the only readily identified genetic cause of chronic obstructive pulmonary disease (COPD). Furthermore, there is growing evidence that even a moderate deficiency increases the risk of lung disease among smokers. Despite these facts, the uptake of testing for AATD in at-risk populations remains low for many reasons, and a lack of clarity among clinicians regarding the most appropriate diagnostic techniques presen...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Publication date: Available online 16 July 2019Source: Journal of Advanced ResearchAuthor(s): Laura Botta, Luigino Dal Maso, Stefano Guzzinati, Chiara Panato, Gemma Gatta, Annalisa Trama, Massimo Rugge, Giovanna Tagliabue, Claudia Casella, Bianca Caruso, Maria Michiara, Stefano Ferretti, Flavio Sensi, Rosario Tumino, Federica Toffolutti, Antonio Giampiero Russo, Anna Luisa Caiazzo, Lucia Mangone, Walter Mazzucco, Silvia IacovacciAbstractThe aims of this study were to provide life expectancy (LE) estimates of cancer patients at diagnosis and LE changes over time since diagnosis to describe the impact of cancer during patien...
Source: Journal of Advanced Research - Category: Research Source Type: research
Publication date: Available online 17 July 2019Source: Academic RadiologyAuthor(s): Henkjan Huisman
Source: Academic Radiology - Category: Radiology Source Type: research
ConclusionIt is feasible to use CNN based algorithm to accurately distinguish cancerous regions in OCT images. This fully automated method can overcome limitations of manual interpretation including interobserver variability and speed of interpretation and may enable real-time intraoperative margin assessment.
Source: Academic Radiology - Category: Radiology Source Type: research
This study explores this question specifically in relation to cultural engagement (e.g. visiting museums/galleries/cinema/theatre/concerts) using data from 8,780 adults aged 50 + from the English Longitudinal Study of Ageing. We used a statistical triangulation approach, running three separate sets of analyses that each have different strengths and address different statistical limitations or biases. Using logistic regression, the relationship between cultural engagement and mental health was still present when including covariates relating to SES, and there was no evidence of moderation by SES either through the...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
Publication date: 1 December 2019Source: Personality and Individual Differences, Volume 151Author(s): Margaret Bennett, Brittny J. LoPresti, Amanda DenesAbstractUsing both attachment theory (Bowlby, 1969) and affection exchange theory (AET; Floyd, 2002), the current study examines the relationships between adult attachment styles, trait affection, post sex affectionate communication behavior, and sexual satisfaction. Through a serial mediation model tested with Hayes' (2013) SPSS PROCESS macro, the findings yield that those with insecure attachment styles have lower levels of trait affection, which predicts less post sex a...
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
Publication date: Available online 16 July 2019Source: Journal of Contextual Behavioral ScienceAuthor(s): Kitty Kioskli, Kirsty Winkley, Lance M. McCrackenAbstractPainful diabetic neuropathy (PDN) is a distressing and disabling condition. There is, surprisingly, relatively little research into the role of psychological variables related to PDN. The aim of this study was to investigate the association between psychological flexibility, daily functioning, and distress in people with PDN. This cross-sectional study included 225 participants who were recruited from hospital services and online. In correlation analyses, accepta...
Source: Journal of Contextual Behavioral Science - Category: Psychiatry & Psychology Source Type: research
In this study, a data processing pipeline for spatially resolved metabolomics analysis of tumor microregion heterogeneity was developed and built into a graphical interface with MSI software. Biological tissue sections were analysed by ambient air-flow assisted desorption electrospray ionization mass spectrometry imaging. Histology-driven and characterized ion images overlay combined with metabolic feature-based spatial segmentation were developed to accurately extract the metabolic profile from the tissue microregion of interest. In addition, appropriate data pretreatment methods were investigated to evaluate their abilit...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
Abstract In cancer diagnostics, specific analysis of blood-circulating proteins biomarkers of cancer is often complicated both by their inherently low concentrations and by strong interference from serum/blood proteins. Here, we report a simple and robust electrochemical cellulase-linked sandwich assay on magnetic beads (MBs) for fM-sensitive analysis of the Human Epidermal growth factor Receptor-2 HER-2/neu protein that is over-expressed in most aggressive breast cancers. In the assay, a sandwich is assembled by capturing HER-2/neu on either antibody (Ab) or aptamer-modified MBs accompanied by reaction with the s...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
We report a case of retinoblastoma regression in the untreated eye following IAC to the contralateral eye.
Source: Saudi Journal of Ophthalmology - Category: Opthalmology Source Type: research
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