Clinical and Pathological Characterization of Lynch-Like Syndrome

Lynch syndrome is characterized by DNA mismatch repair (MMR) deficiency. Some patients with suspected Lynch syndrome have DNA MMR deficiencies but no detectable mutations in genes that encode MMR proteins —this is called Lynch-like syndrome (LLS). There is no consensus on management of patients with LLS. We collected data from a large series of patients with LLS to identify clinical and pathology features.

Source: Clinical Gastroenterology and Hepatology - June 16, 2019 Category: Gastroenterology Authors: Maria Dolores Pic ó, Adela Castillejo, Óscar Murcia, Mar Giner-Calabuig, Miren Alustiza, Ariadna Sánchez, Leticia Moreira, María Pellise, Antoni Castells, Marta Carrillo-Palau, Teresa Ramon y Cajal, Alexandra Gisbert-Beamud, Gemma Llort, Carmen Yagüe Source Type: research