FDA Approves Victoza (liraglutide) for the Treatment of Pediatric Patients 10 Years or Older with Type 2 Diabetes

June 17, 2019 -- The U.S. Food and Drug Administration today approved Victoza (liraglutide) injection for treatment of pediatric patients 10 years or older with type 2 diabetes. Victoza is the first non-insulin drug approved to treat type 2 diabetes...
Source: Drugs.com - New Drug Approvals - Category: Drugs & Pharmacology Source Type: news

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Authors: S A, Gurtoo A, M S, Ap MK Abstract Introduction: Health literacy is the degree to which an individual can obtain, process, understand and communicate about health related information to make informed health decisions. Our aim was to study the influence of Diabetic health literacy in affecting the glycemic control in Diabetic patients. Methodology: This is a Cross sectional Analytical study in 200 diabetic patients. Diabetic Knowledge Test developed by Michigan Diabetic Research and Training Center was modified after appropriate permission and was used to measure health literacy. HbA1C was used as a mea...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusion: There is a need to focus on improving adherence among type 2 diabetes patients and strengthening health care systems for regular supply of medicines and provide health education to the patients and their families emphasising the need of adherence to medications. PMID: 31299834 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Metabolic cycles are a fundamental element of cellular and organismal function. Among the most critical in higher organisms is the Cori Cycle, the systemic cycling between lactate and glucose. Here, skeletal muscle-specific Mitochondrial Pyruvate Carrier (MPC) deletion in mice diverted pyruvate into circulating lactate. This switch disinhibited muscle fatty acid oxidation and drove Cori Cycling that contributed to increased energy expenditure. Loss of muscle MPC activity led to strikingly decreased adiposity with complete muscle mass and strength retention. Notably, despite decreasing muscle glucose oxidation, muscle MPC d...
Source: eLife - Category: Biomedical Science Tags: Cell Biology Human Biology and Medicine Source Type: research
In conclusion, we show here that sEVs are responsible for mediating paracrine senescence and speculate that they could be involved in inducing bystander senescence during therapy-induced senescence or aging. In fact, when compared to soluble factors, sEVs have different biophysical and biochemical properties as they have a longer lifespan than do soluble factors and they are more resistant to protease degradation. The idea that blocking sEV secretion could be a potential therapeutic approach to alleviate senescence "spreading" during chemotherapy-induced senescence or in aging tissues presents itself as a very at...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusions/interpretationFollowing an episode of severe hypoglycaemia managed by EMS, one-fifth of participants required hospital admission, more likely in those with advancing age, increasing comorbidities and injury and one-tenth required EMS again for severe hypoglycaemia in a 3  month period, more likely in those with a greater number of antecedent episodes and lower HbA1c. Knowledge of these factors associated with admission and recurrence provides an opportunity for development of targeted strategies aimed at prevention of severe hypoglycaemia in those most vulnerable.
Source: Diabetologia - Category: Endocrinology Source Type: research
This holds true even in those with a high genetic risk Related items fromOnMedica Weight loss targets exceeded on NHS type 2 diabetes prevention programme Scotland reveals target of halving child obesity by 2030 Public health chiefs set out NHS plan targets Tackling obesity ‘must be made a national priority’ Changing the cultural context of obesity
Source: OnMedica Latest News - Category: UK Health Source Type: news
Scheme to promote 60 minutes of activity daily Related items fromOnMedica Type 2 diabetes in 10 times more young people than realised UK lagging behind peers on child health £1.5m funding for schemes to tackle child obesity We are ‘sitting on a young people’s health time bomb’ Plans revealed to cut excessive calorie consumption
Source: OnMedica Latest News - Category: UK Health Source Type: news
Publication date: Available online 13 July 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Nadia Hamjane, Fatiha Benyahya, Mohcine Bennani Mechita, Naima Ghailani Nourouti, Amina BarakatAbstractAimThe aim of this work was to study overweight and obesity and their associated complications according to obesity indicators in a population of Tangier.MethodsA total of 480 overweight and obese patients were included in this study, referred to hospital Duc Tovar of Tangier during a period of 12 months. The collection of data has been done through a questionnaire which included anthropometric...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionsAll 8 characteristics were shown to significantly influence choice, with cost and life expectancy carrying the most weight and serious and minor side effects carrying the least weight.RésuméObjectifsEstimer la force des préférences, l'importance relative et les compromis que les patients atteints du diabète de type 2 font entre les caractéristiques des antihyperglycémiants.MéthodesNous avons mené une expérimentation de choix discrets auprès d'un échantillon de Canadiens atteints du diabète de type 2. Les répond...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
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