Transnasal Humidified Rapid-Insufflation Ventilatory Exchange for Deep Sedation in a Lung Transplant Candidate With Severe Cystic Fibrosis: A Case Report

We describe the use of transnasal humidified rapid-insufflation ventilatory exchange for deep sedation during dental extractions in a patient with severe cystic fibrosis as a precondition for lung transplantation. Patient wanted to have the procedure under general anesthesia with intubation due to extreme anxiety. However, we advocated deep IV sedation with transnasal humidified rapid-insufflation ventilatory exchange. Oxygenation was maintained without airway obstruction and pulmonary complications during the entire procedure of 110 minutes.
Source: A&A Case Reports - Category: Anesthesiology Tags: Case Reports Source Type: research

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Purpose of review Anxiety and depression (A&D) are common in cystic fibrosis (CF). This review defines A&D in the context of CF and examines our current knowledge about A&D, the impact on CF, treatment and illness trajectory and explores potential areas for prevention. Recent findings CF and A&D are interrelated. The CF diagnosis, symptoms and treatment may trigger symptoms of A&D, leading in some patients, to a clinical diagnosis of anxiety or depression. In return A&D impacts CF, potentially worsening the prognosis, decreasing treatment adherence and overall well being. Research shows how prevention is often imbedde...
Source: Current Opinion in Pulmonary Medicine - Category: Respiratory Medicine Tags: CYSTIC FIBROSIS: Edited by Harry G.M. Heijerman and Nick Simmonds Source Type: research
Children, adolescents, and young adults living with life-threatening serious pediatric illness (SPI) face considerable physical and emotional tolls via their disease conditions, treatment demands, and sequelae. To guide clinical interventions and future research for young people with SPI, Barker and colleagues conducted a meta-analysis to estimate the prevalence of anxiety and depression in children and young people with a variety of SPI, including cancer, cystic fibrosis, HIV, thalassemia, neurological conditions, and chronic kidney disease. The authors found that the prevalence of anxiety and depression is higher among y...
Source: JAMA Pediatrics - Category: Pediatrics Source Type: research
AbstractIndividuals with cystic fibrosis (CF) are confronted by a range of difficult physical and psychosocial sequelae. Gratitude has drawn growing attention as a psychosocial resource, but it has yet to be examined among adults with CF. The current investigation evaluated longitudinal associations between trait gratitude and subsequent outcomes from depression screening 12  months later, adjusting for disease severity (FEV1% predicted) and other significant clinical or demographic covariates. Participants were 69 adult CF patients recruited from a regional adult treatment center. They completed a validated measure o...
Source: Journal of Behavioral Medicine - Category: Psychiatry Source Type: research
Conditions:   Depression;   Anxiety Interventions:   Behavioral: CF-CBT: A Cognitive-Behavioral Skills-Based Program to Promote Emotional Well-Being for Adults wtih Cystic Fibrosis;   Behavioral: Waitlist Control Sponsors:   Massachusetts General Hospital;   Cystic Fibrosis Foundation;   DeltaQuest Foundation, Inc.;   University at Buffalo;   University of Kansas Medical Center;   Stanford University;   Nicklaus Children's Hospital f/k/a Miami Children's Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Depression, Anxiety Interventions:   Behavioral: CF-CBT: A Cognitive-Behavioral Skills-Based Program to Promote Emotional Well-Being for Adults wtih Cystic Fibrosis;   Behavioral: Waitlist Control Sponsors:   Massachusetts General Hospital;   Cystic Fibrosis Foundation;   DeltaQuest Foundation, Inc.;   University at Buffalo;   University of Kansas Medical Center;   Stanford University;   Nicklaus Children's Hospital f/k/a Miami Children's Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Depression;   Anxiety Interventions:   Behavioral: CF-CBT: A Cognitive-Behavioral Skills-Based Program to Promote Emotional Well-Being for Adults wtih Cystic Fibrosis;   Behavioral: Waitlist Control Sponsors:   Massachusetts General Hospital;   Cystic Fibrosis Foundation;   DeltaQuest Foundation, Inc.;   University at Buffalo;   University of Kansas Medical Center;   Stanford University;   Nicklaus Children's Hospital f/k/a Miami Children's Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Depression, Anxiety Interventions:   Behavioral: CF-CBT: A Cognitive-Behavioral Skills-Based Program to Promote Emotional Well-Being for Adults wtih Cystic Fibrosis;   Behavioral: Waitlist Control Sponsors:   Massachusetts General Hospital;   Cystic Fibrosis Foundation;   DeltaQuest Foundation, Inc.;   University at Buffalo;   University of Kansas Medical Center;   Stanford University;   Nicklaus Children's Hospital f/k/a Miami Children's Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Depression;   Anxiety Interventions:   Behavioral: CF-CBT: A Cognitive-Behavioral Skills-Based Program to Promote Emotional Well-Being for Adults wtih Cystic Fibrosis;   Behavioral: Waitlist Control Sponsors:   Massachusetts General Hospital;   Cystic Fibrosis Foundation;   DeltaQuest Foundation, Inc.;   University at Buffalo;   University of Kansas Medical Center;   Stanford University;   Nicklaus Children's Hospital f/k/a Miami Children's Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Tags: Posters Sessions Source Type: research
CONCLUSIONS: We were unable to identify RCTs with evidence which would support healthcare policy-making and practice related to implementation of shared decision-making for children and adolescents (aged between four and 18 years) with CF). We hope that having identified this gap in research, awareness will increase amongst researchers of the need to design high-quality shared decision-making interventions for young people with CF, perhaps adapted from existing models for adults, and to test these interventions and children's preferences in RCTs. It is also important to target health professionals with evidence-based educa...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
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