Cerebral Oximetry Fails as a Monitor of Brain Perfusion in Cardiac Surgery: A Case Report

We present 2 cases where cerebral oximetry failed to accurately portray cerebral oxygenation. In the current form, cerebral oximetry may at best be an expensive tool without any benefit on outcomes. In addition, it may contribute to misleading and confusing clinical data.
Source: A&A Case Reports - Category: Anesthesiology Tags: Case Reports Source Type: research

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CONCLUSIONS: ITP is safe, tolerable, and useful but its inclusion in the multidisciplinary palliative treatment of progressive MPM patients should be investigated in a larger multicentre controlled study. PMID: 31424688 [PubMed - in process]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research
ConclusionsThis agonist did not augment bladder contractility or urethral relaxation in normal rats.
Source: LUTS: Lower Urinary Tract Symptoms - Category: Urology & Nephrology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Source: mAbs - Category: Biomedical Science Authors: Source Type: research
ConclusionsSPECT-MPI using regadenoson is well tolerated in patients with ELD and can help to make decisions about coronary revascularization before lung transplant.
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
ConclusionsPrasugrel in STEMI patients was associated with an increased MSI compared with clopidogrel in the presence of HRPR.
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
AbstractBackgroundThe amelioration of myocardial reperfusion in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PPCI) remains a significant issue.ObjectiveWe conducted a meta-analysis of randomized controlled trials (RCTs) to better assess the effects of intracoronary nicorandil administration on myocardial microcirculation and clinical outcomes in these patients.MethodsThe meta-analysis was performed according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. A literature search was performed in the PubMed, Embase, Cochrane ...
Source: American Journal of Cardiovascular Drugs - Category: Cardiology Source Type: research
Publication date: Available online 18 August 2019Source: Journal of Cardiology CasesAuthor(s): Susumu Odajima, Takumi Inoue, Tomoyo Hamana, Ryota Masaki, Wataru Fujimoto, Koji Kuroda, Yutaka Hatani, Masamichi Iwasaki, Hiroshi Okamoto, Masanori Okuda, Takatoshi HayashiAbstractA 58-year-old woman with pallor on her left hand due to chronic hemodialysis presented with a recent intractable skin ulcer on her left 3rd finger; the skin perfusion pressure (SPP) was 19 mmHg. Preoperative angiography revealed an occluded proximal left radial artery, no communication between the ulnar and superficial palmar arteries, several c...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
This study applies Arterial Spin Labeling (ASL) MRI with a hypercapnic challenge and ex vivo Serial Two-Photon Tomography (STPT) to examine the relationship between blood flow and vascular architecture following traumatic brain injury (TBI) in a mouse. Mice were exposed to a controlled cortical impact TBI and allowed to recover for either 1 day or 4 weeks. At each time point, ASL MRI was performed to quantify cerebral perfusion and the brain vasculature was imaged in 3D with STPT. Registration of ASL to STPT enabled flow changes to be related to the underlying microvascular structure in each ASL voxel. Hypoperfusion under ...
Source: NeuroImage - Category: Neuroscience Source Type: research
Abdominal compartment syndrome (ACS) is an uncommon complication of severe pancreatitis. It is defined as a sustained intraabdominal pressure (IAP)  > 20 mmHg (with or without an abdominal perfusion pressure (A...
Source: BMC Surgery - Category: Surgery Authors: Tags: Case report Source Type: research
DiscussionRenal PC-MRI shows promise as a non-invasive technique to reliably measure RBF, both in healthy volunteers and in patients with renal disease. Future multicentric studies are needed to provide definitive normative ranges and to demonstrate the clinical potential of PC-MRI, likely as part of a multi-parametric renal MRI protocol.
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - Category: Materials Science Source Type: research
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