Laparoscopic Intrapancreatic Accessory Splenectomy: A Case Report of Recurrent Immune Thrombocytopenia in a 33 Years Old Male Patient After 6 Years of Splenectomy

ConclusionThe diagnosis of IPAS can be non-invasively made by an experienced radiologist with the recent advancement of medical imaging. Recognizing IPAS as a possible cause of ITP recurrence, and using minimally invasive approach can be performed safely and lead satisfactory outcomes.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research

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In this study, we characterized the clinical features of SFTS in cats and their associated risk factors, by evaluating the clinical parameters retrospectively. A phylogenetic analysis on SFTSV was also conducted. There were no obvious tendencies in age or sex, outdoor cats were commonly at risk of SFTSV infection. All infected cats showed acute onset of clinical signs including anorexia and lethargy, while 68.2% of the cats showed fever and 41.7% showed vomiting. The case fatality rate was 62.5%. Thrombocytopenia, leukopenia, and elevated serum total bilirubin, serum amyloid A, and creatinine phosphokinase concentration we...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Authors: Tak S, Geethu, Rathore JS, Charan SS, Bijarniya R, Lakhotia M Abstract Objective: To document correlation between vitamin B12 deficiency and severity of thrombocytopenia, platelate recovery and duration of hospital stay in dengue fever patients. Methods: This prospective observationl study was done in dengue fever patient with severe prolonged thrombocytopenia ( 2 days duration). Patient with underlying malignancy, hematological disorders, septicemia, or use of any drug which may cause thrombocytopenia, were excluded. Standard statistical methods were used. Results: Total 40 subjects were included ...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Sarkar R, Paul R, Thakur I, Sau TJ, Roy D, Pandey R, Mani A, Ruia AV Abstract Antiphospholipid antibody syndrome (APS) is an autoimmune disorder, mainly found in young females, presenting with vascular thrombosis and/or obstetric complications. Thrombosis at anatomically significant sites may lead to considerable morbidity and/or mortality. We here present a case of primary APS presenting with sudden onset bilateral multiple cerebral venous sinus thrombosis. The patient, a 17 year old female with no prior rheumatological history, presented with sudden onset bilateral painful blindness and massive proptosis...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
CONCLUSION: Imatinib with low-dose ara-c can be considered as a potential first-line treatment option for CML-CP.
Source: Indian Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
Publication date: Available online 17 July 2019Source: Clinical Lymphoma Myeloma and LeukemiaAuthor(s): Fernando Cabanillas, Noridza Rivera, Mirelis Acosta, Wandaly Pardo, Pedro Solivan, Caroline Rivera, Idalia LiboyAbstractBackgroundOur objective was to evaluate the impact of lenalidomide in patients with aggressive lymphoma who attained
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research
The objective response rate was 8.88% (4/45), and the disease control rate was 88.89% (40/45). The most common grade 3/4 treatment-related AEs were hypertension (12.50%), hand–foot syndrome (6.67%), diarrhea (12.50%), fatigue (6.25%), and proteinuria (14.29%). One drug-related severe AE of thrombocytopenia (21×109/l) occurred 2 months after therapy. Apatinib treatment in our study exhibited objective efficacy in PFS, OS, and manageable toxicity in patients with advanced sarcoma. This result supports future randomized controlled trials to further define apatinib activity in stage IV sarcomas.
Source: Anti-Cancer Drugs - Category: Cancer & Oncology Tags: Clinical Reports Source Type: research
Authors: George N, Sethi P, Nischal N, Kumar A, Siripurapu G, Wig N, Vyas S Abstract A 19 year old boy presented to the emergency room with fever of one week duration along with bleeding manifestations, few gastrointestinal symptoms, tachycardia, tachypnea and subtle encephalitic features. He was worked up for the usual causes of short duration fever, which proved inconclusive. In view of clinical worsening and cytopenias, a careful investigation process helped us in ruling out common etiologies for such a fever, alongwith unearthing the possibility of an underlying secondary hemophagocytic lymphohistiocytosis whic...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusion: Out of 1111 patients with dengue infection, 993 had either thrombocytopenia or hepatic involvement or both. Majority of patients with thrombocytopenia and hepatic dysfunction recovered between 4-7 days of admission i.e 53.98% and 29.20%. Statistically significant corelation of platelet count and aminotransferase levels with recovery or death of the patient was seen in our study. PMID: 31311214 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Immune thrombocytopenia (ITP) in children is one of the most commonly encountered benign hematologic diseases in daily practice for general pediatricians and pediatric hematologists. In general settings, clinical presentations include an incidental finding in an asymptomatic child, abrupt petechiae/ecchymoses, mucocutaneous bleeding, rarely seen life-threatening bleeding, etc.1 During the evaluation phase, an experienced personnel collects detailed history and performs physical examination, complete blood count with differential, and review of peripheral blood smear.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Tags: Editorial Source Type: research
ConclusionsDefinitive CRT with cisplatin and etoposide or carboplatin and etoposide is a feasible treatment for the resectable SCNEC-E, and long-term survival can be achieved in some patients.
Source: Esophagus - Category: Gastroenterology Source Type: research
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