Comparison of BMD Changes and Bone Formation Marker Levels 3 Years After Bisphosphonate Discontinuation: FLEX and HORIZON ‐PFT Extension I Trials

In conclusion, 3 years after bisphosphonate discontinuation, a considerable proportion of former alendronate and zoledronic acid users had meaningful declines in total hip BMD and elevations in PINP. Despite a longer treatment course, alendronate may have a more r apid offset of drug effect than zoledronic acid. © 2018 American Society for Bone and Mineral Research.

Source: Journal of Bone and Mineral Research - May 26, 2019 Category: Orthopaedics Authors: Tiffany Y Kim, Douglas C Bauer, Brian L McNabb, Anne L Schafer, Felicia Cosman, Dennis M Black, Richard Eastell Tags: Original Article Source Type: research