Radiomorphological manifestations of femoral and tibial cortical bones at different stages of limb lengthening
Conclusion: Cortical bone of the femur and tibia in patients with limb length discrepancy and bone deformity of various etiologies showed various preoperative local densities of external, internal, and osteon layers. The cortical bone demonstrated heterogenic structures with resorption areas of various magnitude and density, with minimal values at the boundary with regenerate bone during distraction and fixation with frame on and at short-term followup. Complete organotypical restructuring of the bone was shown to occur at a 1-to-3-year followup depending on the etiology of the disease and amount of lengthening performed.
In conclusion, enchondroma growth was a rare event and typically occurred at two years follow-up in our series. Given the low risk for malignant transformation, we propose surveillance with plain radiographic follow-up for stable enchondromas every 3-6 months for the first year and then annually for at least three years of total follow-up. The most significant costs savings can be made by limiting MRI imaging in the absence of clinical or radiographic concern. Additional studies are needed to determine the long-term risk of growth or declaration of chondrosarcoma.Level of Evidence: IV. PMID: 31413693 [PubMed - in process]
Discussion PSMA PET-CT imaging may have a substantial impact on clinical management in prostate cancer patients at the time of initial staging or with biochemical failure; yet this modality does not appear useful in the management of patients with known metastatic disease.
Conclusion Stability in tumour SUVmax values measured at different intervals independently of tumour location, as also in normal tissues as kidneys and liver suggest that a more flexible imaging protocol may be adopted.
Conclusions The sensitivity of TOF [F-18]FDG-PET/CT was as high as 85% by visual analysis. SUVmax using TOF [F-18]FDG-PET/CT showed high diagnostic performance for N-staging in breast cancer patients, especially high negative predictive value. The specificity, positive predictive value and accuracy of SUVmax were higher than those of visual analysis.
Authors: Jiang T, Zhao Q, Tian G, Chen X, Wu L Abstract Metastatic retroperitoneal tumors constitute an end-stage disease with poor prognosis that represents a heavy global health burden. The present study aimed to explore the efficacy of irreversible electroporation ablation (IRE) therapy in patients with end-stage retroperitoneal tumors. Between April 2016 and September 2017, three patients with unresectable retroperitoneal malignant tumors were enrolled. Among these cases, ultrasound (US)-guided IRE was palliatively performed for targeting 3 tumors (1 tumor per patient) located around the abdominal aorta. Post-t...
ConclusionsEarly SOS widening could be identified in the lowest part before median palatal suture opening. Similarly, narrowing of the SOS at its top was observed before the most significant median palatal suture expansion. Thus it can be hypothesized that changes within the SOS complex result from the transmission of the orthopaedic forces rather than from a displacement of the maxillary halves.
This article begins by providing an overview of the MMP subfamily and its structure and function. The latest advances in the design of subtype selective MMPIs and their biological evaluation are then summarized. Subsequently, the potential use of MMPI-labeled diagnostic agents in clinical imaging techniques are discussed, including positron emission tomography (PET), single-photon emission computed tomography (SPECT) and optical imaging (OI). Finally, this article concludes with future perspectives and clinical utility.
ConclusionSevere maxillofacial fracture should be treated immediately to avoid further complications. Multidisciplinary examinations can provide more accurate preliminary recommendations particularly when combine with properly calibrated CT scan imaging.
Publication date: October 2019Source: Epilepsy &Behavior, Volume 99Author(s): Ravindra Arya, Brian Ervin, Jonathan Dudley, Jason Buroker, Leonid Rozhkov, Craig Scholle, Paul S. Horn, Jennifer Vannest, Anna W. Byars, James L. Leach, Francesco T. Mangano, Hansel M. Greiner, Katherine D. Holland, Tracy A. GlauserAbstractObjectiveWe prospectively validated stereo-electroencephalography (EEG) electrical stimulation mapping (ESM) of language against a reference standard of meta-analytic functional magnetic resonance imaging (fMRI) framework (Neurosynth).MethodsLanguage ESM was performed using 50 Hz, biphasic, bipolar, stim...
Publication date: Available online 14 August 2019Source: Interdisciplinary NeurosurgeryAuthor(s): Kara L. Krajewski, Silvia Hernández-Durán, Jakob Matschke, Tammam AbboudAbstractWe demonstrate two unusual cases of malignant swelling and rapid fatal outcome as a form of the “wounded glioma syndrome” after biopsy of diffuse anaplastic gliomas in two young men.In the first case, the lesion was throughout the right temporal, parietal and occipital lobes and extending into the basal ganglia with a small contrast-enhancing lesion in the temporal lobe. The patient underwent an open biopsy of the contrast...