Brain fever kills 97 children in east India

Nearly 100 children have died this month from encephalitis, commonly known as brain fever, in the eastern Indian state of Bihar, a state health official said on Monday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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We report a case of a middle aged seropositive male, virologically well suppressed on second line ART (Anti-Retroviral therapy) who presented with a subacute history of neurological symptoms. On imaging and CSF (cerebrospinal fluid) evaluation, he was found to have CD8 encephalitis - a new, rare but treatable entity. To the best of our knowledge, no case has been reported from India. PMID: 31324097 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
(Vanderbilt University Medical Center) The results, published July 22 in Nature Medicine, are the latest findings by VICC researchers chronicling rare but serious toxicities that may occur with immune checkpoint inhibitors, the most widely prescribed class of immunotherapies.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
ConclusionsThis case provides further evidence for the occurrence of NMOSD with AQP4-IgG-seropositive overlapping anti-NMDAR encephalitis in a Chinese patient. The mechanisms underlying the occurrence of double positive antibodies remains elusive. When NMOSD patients show unusual symptoms (abnormal behavior, prominent psychiatric manifestations, cognitive dysfunction, autonomic dysfunction), or atypical supratentorial lesions, the coexistence of anti-NMDAR encephalitis should be considered.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: Available online 20 July 2019Source: Multiple Sclerosis and Related DisordersAuthor(s): Jennifer Massey, Yael Barnett, Jennifer Curnow, Ian SuttonAbstractSecondary autoimmune disorders (AID) are a recognised complication of alemtuzumab treatment for multiple sclerosis. We have previously reported two female multiple sclerosis patients treated with alemtuzumab who developed rare but severe secondary AID; acquired haemophilia A and autoimmune encephalitis with seizures. Both cases proved to be refractory to treatment with conventional immuno-therapy. However, treatment of the patients with anti-CD20 therapy...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
rtin Beer Tick-borne encephalitis virus (TBEV) is an important arbovirus, which is found across large parts of Eurasia and is considered to be a major health risk for humans. Like any other arbovirus, TBEV relies on complex interactions between vectors, reservoir hosts, and the environment for successful virus circulation. Hard ticks are the vectors for TBEV, transmitting the virus to a variety of animals. The importance of these animals in the lifecycle of TBEV is still up for debate. Large woodland animals seem to have a positive influence on virus circulation by providing a food source for adult ticks; birds are sus...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Conclusion: A subacute onset, rapidly progressive painful, pure motor quadriparesis; Ganglionopathy in elderly and autoimmune encephalitis with ill sustained or no response to corticosteroids merits consideration of paraneoplastic etiology. PMID: 31321924 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Publication date: Available online 19 July 2019Source: Journal of Clinical NeuroscienceAuthor(s): Lu Yao, Wang Yue, Wu Xunyi, Wang Jianhong, Zhu Guoxing, Hong ZhenAbstractPurposeTo evaluate the clinical characteristics, treatment outcomes, prognosis and potential risk factors of patients in East China with seizure secondary to autoimmune encephalitis.MethodsFrom February 2014 to June 2016, 113 patients diagnosed with autoimmune encephalitis in Huashan Hospital, Fudan University, were enrolled in our study. After at least two years of follow-up, we retrospectively analyzed the patients’ clinical details, electroenceph...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
In conclusion, we provide here an approach to control the genetic diversity of RNA viruses without modifying their phenotype.
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is the most common type of autoimmune encephalitis, mostly affecting young patients. In children, movement disorders are the predominant manifestation of anti-NMDA receptor encephalitis including chorea, stereotypies, tremor, myoclonus and generalized dystonia [1]. Herein we report a case of anti-NMDA receptor encephalitis presenting with status dystonicus (SD) resistant to immunosuppressive therapies who responded well to bilateral Globus Pallidus Internus (GPi) deep brain stimulation (DBS).
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Tags: Correspondence Source Type: research
FRIDAY, July 19, 2019 -- In the July 19 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report, recommendations are presented for use of the Japanese encephalitis (JE) vaccine. Susan L. Hills, M.B.B.S.,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
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