High Soy Intake May Cut Fracture Risk in Younger Breast Cancer Survivors

Findings seen among pre - /perimenopausal survivors of stage 0 to III breast cancer
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Endocrinology, Family Medicine, Geriatrics, Gynecology, Internal Medicine, Nursing, Oncology, Orthopedics, Rheumatology, Journal, Source Type: news

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Breast cancer causes high mortality among females worldwide. Bufalin has recently been shown to trigger tumor cell death, although the mechanism of cytotoxicity remains unclear. The cytotoxicity of bufalin in breast cancer cells was examined using an MTT assay. The modes of death and intracellular reactive oxygen species production were measured by flow cytometry. We also observed cellular morphologic changes by Hoechst 33342 and propidium iodide staining and transmission electron microscopy. Western blotting was performed to determine the expression levels of related proteins. Our results showed that bufalin reduced cellu...
Source: Anti-Cancer Drugs - Category: Cancer & Oncology Tags: Preclinical Reports Source Type: research
Publication date: November 2019Source: Materials Science and Engineering: C, Volume 104Author(s): Abdolhossien Miri, Nafiseh Mahdinejad, Omolbanin Ebrahimy, Mehrdad Khatami, Mina SaraniAbstractZinc oxide nanoparticles (ZnO-NPs) are multifunctional oxide metal nanoparticles that have been considered by many due to their unique properties including UV filtration, semiconducting, antimicrobial, antifungal, and photocatalytic activity. In the present study, ZnO-NPs have been synthesized from Zn(SO4)·7H2O through the use of “green synthesis” method that utilizes Prosopis farcta aqueous extract. The characteri...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: Available online 18 July 2019Source: NeurocomputingAuthor(s): Runze Wang, Yide Ma, Wenhao Sun, Yanan Guo, Wendao Wang, Yunliang Qi, Xiaonan GongAbstractMass segmentation in mammograms is an important and challenging topic in breast cancer computer-aided diagnosis. In this work, we propose a novel multi-level nested pyramid network (MNPNet) for dealing with the limitations of intra-class inconsistency and inter-class indistinction that commonly existed in mass segmentation in mammograms. The MNPNet includes an encoder and a decoder. The former encodes contextual information, low-level detail information, a...
Source: Neurocomputing - Category: Neuroscience Source Type: research
The objective of this study is to explore whether the utilization of PMBR varies by race, marital status, and geographical location of the patient.MethodsWomen ≥18 years old who underwent mastectomy for breast cancer diagnosed between 2000 and 2014 were eligible. Women with inflammatory BC, Stage IV BC diagnoses, and bilateral BC were excluded. Multivariable logistic regression, adjusting for patient and cancer characteristics, were used to assess the association between of race, marital status, and region on immediate PMBR utilization.Results321,206 women were included and 24% underwent immediate PMBR (
Source: The American Journal of Surgery - Category: Surgery Source Type: research
ConclusionsSelective WBXRT may have mitigated LR. Nearly all LR were in patients not recommended WBXRT. Further work should refine criteria for WBXRT after IORT.SummaryPrior work among women with early breast cancer supported lumpectomy with intraoperative radiation therapy and selective adjuvant radiation using a risk-adapted approach. An expanded set of criteria for adjuvant radiation appear to further mitigate local recurrence risk. Local recurrence after lumpectomy with IORT could be further minimized by identification of additional high-risk features, as well as greater adherence to adjuvant endocrine therapy.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
Source: Anti-Cancer Agents in Medicinal Chemistry - Category: Cancer & Oncology Authors: Tags: Research article Source Type: research
This study aimed to develop and evaluate a training program for occupational health nurses (OHNs) regarding support for workers with cancer and their workplaces. METHODS: Based on our prior research, we engaged in multiple discussions on the development of training program for OHNs. For examining the effectiveness of the developed training program, we collected and analyzed the data from three repeated surveys conducted before, immediately after, and 3 months after the training on self-confidence levels of the participants regarding 23 items associated with support for workers with cancer and their workplaces. ...
Source: Journal of Occupational Health - Category: Occupational Health Tags: J Occup Health Source Type: research
Researchers examined the germline DNA of Hispanic women with BRCA-negative breast cancer to pinpoint pathogenic variants.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
(IDIBELL-Bellvitge Biomedical Research Institute) Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify methylation patterns associated with different subtypes of breast cancer, and a subclassification of the group of " triple negatives " , a breast cancer type typically associated with poor prognosis. In addition, researchers identified changes in DNA methylation associated with the response to docetaxel, a common therapy. The research was led by Dr. Eva Gonz á lez-Su á rez, head of the IDIBELL Transformation a...
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
(Northwestern University) Many of the deadliest or most common cancers get the least amount of nonprofit research funding, reports a new Northwestern Medicine study. 'Embarrassing' or stigmatized cancers, like lung and liver, are underfunded. Colon, endometrial, liver and bile duct, cervical, ovarian, pancreatic and lung cancers were all poorly funded compared to how common they are and how many deaths they cause, the study found. In contrast, breast cancer, leukemia, lymphoma and pediatric cancers were all well-funded, respective to their impact on society.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
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