Orthopaedic Surgery Trend in Rheumatoid Arthritis - results of the National Registry of Hospitalised Patients (CMBD) over a 17 year period (1999-2015). TREND-AR Study.

CONCLUSION: Although the overall OS rate has not changed, there is a decrease in the rate of arthrodesis at all ages, THA in patients under 80 years of age, as well as TKA and ULA in patients under 60 years of age. PMID: 31203231 [PubMed - as supplied by publisher]
Source: J Rheumatol - Category: Rheumatology Authors: Tags: J Rheumatol Source Type: research

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Authors: Nagpal SDS, Singh NP, Mishra P, Singh A Abstract Rheumatoid arthritis (RA) is a common rheumatological condition affecting the joints and has a wide range of extra-articular manifestations. A 69 year old male, known case of rheumatoid arthritis presented to our OPD with right lower limb redness and swelling, and left axillary lymph node swelling. Lymph node biopsy revealed a high grade diffuse large B-cell lymphoma with co-expression of c-myc and bcl-2 (double expressor). RA increases the risk of both Hodgkin's lymphoma (HL) and non-Hodgkin's Lymphoma (NHL). The association with diffuse large B-cell lympho...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
MONDAY, July 22, 2019 -- Six-month sustained remission (SR) is not uncommon in patients with rheumatoid arthritis (RA), according to research published online July 12 in the International Journal of Rheumatic Diseases. Wenhui Xie, from Peking...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Results from a one-year study suggest subcutaneous CT-P13, which is biosimilar to infliximab, is as safe and effective for RA patients as intravenous (IV) CT-P13 and IV infliximab...
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Biologics & Biosimilars Drug Updates CT-P13 EULAR infliximab Rheumatoid Arthritis (RA) Source Type: research
Source: Patient Preference and Adherence - Category: International Medicine & Public Health Tags: Patient Preference and Adherence Source Type: research
ObjectiveRheumatoid arthritis (RA) is associated with increased cardiovascular event (CVE) risk. The impact of statins in RA is not established. We assessed whether atorvastatin is superior to placebo for the primary prevention of CVEs in RA patients.MethodsA randomized, double ‐blind, placebo‐controlled trial was designed to detect a 32% CVE risk reduction based on an estimated 1.6% per annum event rate with 80% power atP50 years or with a disease duration of>10 years who did not have clinical atherosclerosis, diabetes, or myopathy received atorvastatin 40 mg daily or matching placebo. The primary end point was a c...
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Original Article Source Type: research
ObjectiveTo examine and quantify the sexual dimorphism in pathologic features manifested in the musculoskeletal and cardiopulmonary systems and incidence of mortality in the tumor necrosis factor –transgenic (TNF‐Tg; Tg3647 strain) mouse model of inflammatory erosive arthritis.MethodsKaplan ‐Meier survival estimates were determined in male and female Tg3647 mice and sex‐matched wild‐type (WT) littermate mice. Longitudinal and cross‐sectional pathologic outcomes in the musculoskeletal and cardiopulmonary systems were assessed via ultrasound, micro–computed tomography, grip str ength measurements, histo...
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Original Article Source Type: research
Arthritis&Rheumatology, EarlyView.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Clinical Images Source Type: research
AbstractAimInflammatory joint diseases (IJDs) are chronic arthritis, but frequently present with co ‐morbidities of other organs and systems, which is known as extra‐articular manifestations (EAMs). It is still unclear which clinical characteristics or bio‐markers can predict the development of EAMs. The aim of this study was to estimate the proportion of EAMs in southern Chinese patients wi th IJDs and to explore the risk factors.MethodsThis was a retrospective cohort study of a total 1135 IJDs patients, including 788 rheumatoid arthritis (RA) patients, 307 ankylosing spondylitis (AS) patients and 40 psoriatic arthr...
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: ORIGINAL ARTICLE Source Type: research
In conclusion, modulation of miR‑145‑5p expression is potentially useful for the treatment of RA inflammation, by regulating the expression of MMPs, and MMP‑9 in particular, through inhibition of the NF‑κB pathway. PMID: 31322192 [PubMed - as supplied by publisher]
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Conclusion. EA on ST36 and GB39 acupoints can effectively inhibit synovial angiogenesis in the AA rat model via downregulating HIF-1α/VEGF expression. PMID: 31316573 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
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