Manual Therapy With Cryotherapy Versus Kinesiotherapy With Cryotherapy for Knee Osteoarthritis: A Randomized Controlled Trial.

Conclusion: The patients achieved better health benefits from manual therapy when it was combined with cryotherapy. PMID: 31202210 [PubMed - in process]
Source: Alternative Therapies in Health and Medicine - Category: Complementary Medicine Authors: Tags: Altern Ther Health Med Source Type: research

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No abstract available
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Letters to the Editor Source Type: research
Accumulation of senescent cells with age is one of the causes of aging. In recent years, the broader scientific community has become convinced of this point, and thus funding is now directed towards many varied investigations of cellular senescence and what to do about it. A young industry has emerged, made up of biotech companies focused on the selective destruction of senescent cells, mostly using small molecule drugs. Since these drugs operate through different mechanisms, tend to be tissue specific, only clear a fraction of senescent cells that varies by tissue, and will thus probably be more effective when combined to...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
A meta-analysis confirms prior research suggesting exercise therapy benefits patients with knee and hip osteoarthritis (OA). The study found greater improvements in pain, function, performance and quality of life in patients with milder, as opposed to more severe, OA...
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions Osteoarthritis Exercise Exercise/physical therapy hip knee Knee Osteoarthritis (OA) Source Type: research
We aimed to investigate mechano-sensitivity at the afferent nerve fibers projecting to degenerated intervertebral disc (IVD) and nociceptive behaviour in a rat model of low back pain (LBP).
Source: Osteoarthritis and Cartilage - Category: Rheumatology Authors: Source Type: research
Condition:   Ankle Osteoarthritis Intervention:   Other: PRP Sponsor:   Kaohsiung Veterans General Hospital. Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This popular science article from the AARP is representative of the sort of outsider's view of the longevity industry that is presently dominant. On the one hand, it is good that the media and advocacy organizations such as AARP are finally talking seriously about treating aging as a medical condition. On the other hand, the author looks at two of the most popular areas of development, mTOR inhibitors and senolytics, in a way that makes them seem more or less equivalent, and then further adds diet and exercise as another equivalent strategy. This will be continuing issue, I fear. People, as a rule, don't think about size o...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
ObjectiveTo assess the efficacy and safety of high ‐purity synthetic trans‐capsaicin (CNTX‐4975) in patients with chronic moderate‐to‐severe osteoarthritis (OA)–associated knee pain.MethodsIn this phase II multicenter double ‐blind study, patients ages 45–80 years who had stable knee OA were randomized in a 2:1:2 ratio to receive a single intraarticular injection of placebo, CNTX‐4975 0.5 mg, or CNTX‐4975 1.0 mg. The primary efficacy end point was area under the curve (AUC) for change from baseline in daily West ern Ontario and McMaster Universities Osteoarthritis Index pain with walking score (...
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Original Article Source Type: research
Herbs that may help reduce joint pain include eucalyptus, aloe vera, and turmeric. People can take these herbs in a variety of forms. Learn more about the best herbs for joint pain here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Osteoarthritis Source Type: news
Conditions:   Knee Osteoarthritis;   Total Knee Arthroplasty (TKA) Intervention:   Sponsor:   NorthShore University HealthSystem Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
To evaluate contextual effects in the form of placebo responses (PRs) for patient-reported pain and function and objectively measured function in osteoarthritis (OA) clinical trials.
Source: Arthritis Research and Therapy - Category: Rheumatology Authors: Tags: Review Source Type: research
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