Acute isolated aphasia as a challenging symptom in the emergency setting: Predictors of epileptic mimic versus ischemic stroke

ConclusionsOur study underscores the importance of an accurate clinical bed-side assessment as the first step in the diagnostic and therapeutic decision-making process for patients presenting with aphasia. The detection of clinical and anamnestic features associated with an epileptic SM could be useful for the diagnostic process and for time-critical treatments.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research

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Publication date: Available online 20 July 2019Source: Journal of Clinical NeuroscienceAuthor(s): Pornpatr A. Dharmasaroja, Nattaphol Uransilp, Pritsana PiyabhanAbstractThe anatomic variation of Circle of Willis (CW) has been shown to have a great impact on its compensatory capacity during acute ischemic stroke. The purpose of the study was to evaluate the effect of variations in CW on collateral circulation in patients with acute ischemic stroke who had major artery occlusion. Patients with acute ischemic stroke within 4.5 h of stroke onset who had at least moderate severity of stroke (NIHSS ≥ 6), caused by major...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
ConclusionsA bleeding revision is associated with significantly reduced survival and substantially increased morbidity during LVAD support. Preoperative, intraoperative, and postoperative prophylactic strategies may help to prevent this life-threatening complication.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsThe use of physician-modified thoracic stent grafts for the treatment of dissecting aortic arch aneurysm after surgical treatment of acute type A dissection is feasible and effective. Durability concerns will need to be assessed in future studies.Visual Abstract
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
ConclusionsIn our experience, this approach is a reliable platform for a variety of MICS procedures and has resulted in low complication rates. The technique can be applied safely to both paediatric and adult population. Also, it is very cost effective as regular instruments and cannulas are used.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Conclusions: Although persons with AD are often collectively considered as expensive patient group, there is large temporal and inter-individual variation in belonging to the highest decile of hospitalization and/or medication costs. It would be important to assess whether hospitalization rate could be decreased by, e.g., comprehensive outpatient care with more efficient management of comorbidities. In addition, other interventions that could decrease hospitalization rate in persons with dementia should be studied further in this context. Key messages Persons with AD had large individual fluctuation in hospital care costs ...
Source: Annals of Medicine - Category: Internal Medicine Tags: Ann Med Source Type: research
ConclusionDespite the use of AEDs in the majority of patients, only one-third were seizure-free. Other challenges included polypharmacy, the use of valproate in women, and variable adherence. This points to a need for closer follow-up in patients with JME.Graphical abstract
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Authors: Miao Y, Wang R, Wu H, Yang S, Qiu Y Abstract The current study used a rat middle cerebral artery occlusion (MCAO) model with the aim to explore the effects of compound porcine cerebroside and ganglioside injection (CPCGI) on brain ischemia/reperfusion injury in rats. Improvement in the infarct‑side microcirculation and the overall recovery of neurological function were detected by triphenyltetrazolium chloride staining, laser speckle blood flow monitoring, latex perfusion, immunofluorescence and immunoblotting. The results revealed that administration of CPCGI for 7 consecutive days following i...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
CONCLUSIONS: Our study demonstrates no additional value of motor evoked potential amplitude of the affected EDC muscle to the clinical test of finger extension, the latter being more strongly related to FMA_UE26. PMID: 31322583 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - Category: Neurology Tags: Restor Neurol Neurosci Source Type: research
This article reviews purine nucleoside production in ischemia, the development of purine analysis technology and details results of the studies investigating purine nucleosides as a biomarker of ischemia with suggestions for areas of future research. PMID: 31321992 [PubMed - as supplied by publisher]
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
Publication date: Available online 22 October 2018Source: Neurología (English Edition)Author(s): C. Avellaneda-Gómez, A. Rodríguez Campello, E. Giralt Steinhauer, A. Gómez González, M. Serra Martínez, P. de Ceballos Cerrajería, A. Zabalza de Torres, E. Cuadrado-Godia, A. Ois Santiago, J. Jiménez-Conde, J. RoquerAbstractIntroductionA considerable percentage of events initially diagnosed as ischaemic stroke have non-cerebrovascular causes; these are called stroke mimics (SM). Currently available evidence about these events is heterogeneous and comes from studies with sm...
Source: Neurologia - Category: Neurology Source Type: research
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