ILCs in hematologic malignancies: Tumor cell killers and tissue healers.

ILCs in hematologic malignancies: Tumor cell killers and tissue healers. Semin Immunol. 2019 Jun 11;: Authors: Blom B, van Hoeven V, Hazenberg MD Abstract Innate lymphoid cells (ILCs) have attracted considerable attention in the past years. As modulators of epithelial barrier immunology and homeostasis they play important roles in (auto)immunity and inflammation. Here we review the role of ILCs in hematologic malignancies, where ILCs act as efficient killer cells and as tissue healers, in the context of chemotherapy, radiotherapy and after allogeneic hematopoietic stem cell transplantation (HSCT). PMID: 31200953 [PubMed - as supplied by publisher]
Source: Seminars in Immunology - Category: Allergy & Immunology Authors: Tags: Semin Immunol Source Type: research