Ivermectin decreases triglyceride accumulation by inhibiting differentiation of 3T3-L1 preadipocytes.

In conclusion, ivermectin inhibits adipogenesis of 3T3-L1 preadipocytes partially via PPARγ & GlyR-dependent, but not FXR-dependent, pathway. PMID: 31199990 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31199990?dopt=Abstract

Source: Food and Chemical Toxicology - June 10, 2019 Category: Food Science Authors: Qi W, Clark JM, Suvorov A, Park Y Tags: Food Chem Toxicol Source Type: research