Making NSC and Neurons from Patient-Derived Tissue Samples.

We describe a method of deriving NSCs and differentiated mature neurons highlighting key steps of the core protocol. We also provide detailed information of the transcription factor and morphogen map of the developing brain which can be used as a guide to derive region- and lineage-specific NSCs and differentiated neurons. PMID: 30656618 [PubMed - indexed for MEDLINE]

https://www.ncbi.nlm.nih.gov/pubmed/30656618?dopt=Abstract

Source: Mol Biol Cell - June 16, 2019 Category: Molecular Biology Authors: Mukherjee O, Acharya S, Rao M Tags: Methods Mol Biol Source Type: research