Calcium receptors located in fibrotic septa: a new target to reduce portal pressure in liver cirrhosis

In conclusion, the present study provides evidence that in experimental cirrhosis agonists of liver CaRs elicit beneficial portal hypotensive effects by reducing intrahepatic resistance to portal flow. Moreover, these drugs are devoid of effects on systemic hemodynamics.
Source: Clinical Science - Category: Biomedical Science Authors: Source Type: research