Reply to the Letter to the Editor on "Continuous Antibiotic Therapy Can Reduce Recurrence of Prosthetic Joint Infection in Patients Undergoing 2-Stage Exchange" by Casta ño et al..

Casta ño et al. raise some question on the methodology of our recent paper investigating the usefulness of an antibiotic-free period prior to reimplantation in patients with Prosthetic Joint Infection (PJI) undergoing 2-stage procedure. Main questions are that the response rate obtained for patients unde rgoing definitive reimplantation after an antibiotic holiday period was lower than reported in their Literature analysis and that the difference reported was not attributable to the effect of continuous therapy, but to the surgical procedure (1).

Source: The Journal of Arthroplasty - June 14, 2019 Category: Orthopaedics Authors: Ascione T, G. Balato, Pagliano P Source Type: research