The protective effects of glucagon ‐like peptide‐1 on cardiac remodeling by inhibiting oxidative stress through mammalian target of rapamycin complex 1 /p70 ribosomal protein S6 kinase pathway in diabetes mellitus

ConclusionsGLP ‐1 protects the cardiomyocyte from oxidative stress and apoptosis in DM, which may contribute to the improvement of cardiac remodeling. The cardiac protection of GLP‐1 may be dependent on inhibition of mTORC1/p70S6K, via an AMPK‐mediated pathway.This article is protected by copyright. All rights reserved.
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Original Article Source Type: research