A Design of experiments Approach to Assess the Effect of Formulation and Process Variables on the Extrusion and Spheronization of abhrak bhasma Loaded spheroids

Publication date: 2019Source: Materials Today: Proceedings, Volume 15, Part 2Author(s): Harish Gopinath, Murugesh ShivashankarAbstractThe aim of the current study is to determine the composition and process parameters and also to optimise formulation of spheriods using blanket burman design. The DoE study conducted using 3nos of Categorical factors and 8nos of numerical factor. Based on the outcome of the placebo DoE studies, the optimised formulation of the abhrak bhasma spheroids had been formulated and evaluated for its Invitro activity in cell lines..
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research