Effects of Cardiac Hypertrophy, Diabetes, Aging, and Pregnancy on the Cardioprotective Effects of Postconditioning in Male and Female Rats.
Conclusions: We demonstrate that aging, LVH, diabetes mellitus, and pregnancy do not affect cardiac vulnerability to ischemic insult. Moreover, PPC mediates cardioprotection in a gender-specific manner in aged and spontaneously hypertensive rats. Diabetes mellitus provokes the protective effects of PPC on both genders equally. Finally, we demonstrate that PPC is a new cardioprotective maneuver in hearts from pregnant female rats.
PMID: 31198607 [PubMed]
Source: Cardiology Research and Practice - Category: Cardiology Authors: Babiker F, Al-Jarallah A, Al-Awadi M Tags: Cardiol Res Pract Source Type: research
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