Observations of Autonomic Variability Following Central Neuromodulation for Chronic Neuropathic Pain in Spinal Cord Injury

ConclusionsCentral modulation targeting the PNM produced autonomic changes in SCI  + NP persons but not AB persons. These findings suggest that AB persons exhibit intact CAN mechanisms capable of compensating for PNM aberrations or simply that SCI + NP persons exhibit altered PNM‐CAN machinery altogether. Our collective findings confirm the interconnectedness and malada ptive plasticity of PNM‐CAN machinery in SCI + NP persons and suggest that the PNM and CAN circuitry can be differentially modulated.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Clinical Research Source Type: research